Why do women and younger people have more side effects due to the vaccination against Pfizer or Moderna? UCSF doctor explains

SAN FRANCISCO – For 24 hours, these were the side effects Irma Duran went through after her second Pfizer shot.

“I shot at 10:30 in the morning and then woke up at midnight. I had a high fever and my legs … It felt like sandpaper. Like someone rubbing my legs,” Duran said.

A San Francisco expert from the University of California says these side effects after the second COVID-19 shot are normal because the immune response to the second shot is stronger.

“It’s the peak protein that deceives the mRNA to produce the cells. It’s being observed. That’s what we want it to do. It’s all right,” said George Rutherford, a professor at UCSF and Epidemiology and Biostatistics.

In this CDC report, data shows that out of 13.7 million Americans vaccinated during December and January of 2021, it was higher among women.

78.7% of reports were submitted for side effects in women. Headache (22.4%), fatigue (16.5%) and dizziness (16.5%) were the most commonly reported symptoms after vaccination with one Sixty-two reports of anaphylaxis have been confirmed, 46 (74.2%) after receiving the Pfizer-BioNTech vaccine and 16 (25.8%) after receiving the Moderna vaccine. ‘

Luz Pena: “Why do women and young adults have more reactions to the second shot of the Moderna or Pfizer vaccine?”

Dr. Rutherford: “Women need to have stronger immune responses because they need to protect pregnancies. They need to live to have babies. It probably has to do with sex hormones. I can not tell you the exact biochemical mechanism, but it makes perfect sense if you think about it in that larger context, “and added,” We also know that the immune system gets older and accumulates problems as you get older, but it’s not at all surprising to me that the reactions are more common in younger people older people. “

Let us now be clear that these side effects are mild and usually last between two and three days. These are in some cases headaches, body aches and fever.

Should people worry if they do not have any of the vaccines?

“No. There is nothing wrong with them. They just have a better regulated immune system that they can get through without causing a lot of unnecessary symptoms. If you do not feel these symptoms, there is no reason for you to have antibody test,” the dr. Rutherford said.

San Francisco resident Alejandro Galicia, 34, felt the side effects of the first Moderna shot. He was hospitalized with COVID-19 a year ago and has a 50% chance of survival. He puts the body hurt after his first shot in perspective.

“Mentally, it brings you back to fever and it’s just psychological, but then you tell yourself it’s nothing compared to COVID,” Galicia Diaz said.

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