US Coronavirus: Uncontrolled distribution of Covid-19 increases the chance of a more dangerous variant emerging, says former CDC chief

“We have to act now, and I’m worried that if we do not take the right steps now, we will have another inevitable boom – just as we currently see in Europe and just as aggressively scale up vaccination, Rochelle Walensky, director of the Center for Disease Control and Prevention, said Monday.

And a high level of infection could also mean vaccination problems later, an expert told CNN on Monday.

“Not only does uncontrolled spread cause preventable diseases, hospitalization and death, but it increases the risk of an even more dangerous variant that could make the vaccine less effective,” said Dr Tom Frieden, the former CDC director. .

You asked, we answered: Your most important questions about Covid-19 and vaccines

Travel and crowds usually lead to congestion

While vaccines are being rolled out, Frieden says Americans should continue to take precautions, such as wearing masks and restricting travel and leisure time with people who are not from their household.

Springbreakers flock to South Florida, while some residents worry about another Covid-19 boom

“When people travel and mix, you can see a huge increase in infections a few weeks later,” he adds.

Despite the warnings from health officials – some Americans do both.
The Transport Security Administration on Sunday selected more than 1.5 million people at airports nationwide – a new record of the pandemic era that passes the pace set just two days earlier.
Meanwhile, the springbreakers are flocking to popular destinations such as Florida, where officials in Miami Beach have declared a state of emergency and imposed a curfew rule in response to the crowd the mayor said ‘is more than we can handle’.
All this while governors and local leaders across the country are easing Covid-19 restrictions, to curb the spread of the virus.
Follow Covid-19 cases in the US
People enjoy themselves as they walk along Miami Drive in Miami Beach, Florida on March 18, 2021

Vaccinations have saved thousands of lives

Frieden says he believes the US is likely to see another boom, but it will be ‘much less lethal’ due to the vaccines being administered.

To date, more than 82.7 million Americans have received at least one dose of Covid-19 vaccine and more than 44.9 million have been completely vaccinated, according to CDC data.

“We estimate that vaccination has already saved at least 40,000 lives in the US,” Frieden said. “These are really good vaccines and the faster we get them out.”

Krispy Kreme makes vaccinations extra sweet with a free donut a day for the rest of the year
Three Covid-19 vaccines have so far received the green light from the US Food and Drug Administration – Pfizer, Moderna and Johnson & Johnson, the only one of the three that require a single shot.
And a fourth vaccine may be on the way soon. AstraZeneca is expected to apply for emergency use consent for the vaccine within the next few weeks.
The AstraZeneca vaccine has shown 79% efficacy against symptomatic diseases and 100% efficacy against serious diseases and hospitalization in a new US clinical trial, the company said on Monday.
However, the independent council reviewing the data of several Covid-19 vaccine candidates has expressed concern about the findings, according to a statement released early Tuesday by the National Institute of Allergy and Infectious Diseases.

The Data and Security Monitoring Board “expressed concern that AstraZeneca may have contained outdated information from the trial, which could have provided an incomplete overview of the efficacy data,” the statement said.

“We call on the company to work with the DSMB to review the efficiency data and ensure that the most accurate, up-to-date efficiency data is released as soon as possible,” he said.

Earlier, AstraZeneca said it hopes to deliver 50 million doses within a month if authorized for emergency use.

“We plan to submit to the FDA in the first half of April, assuming that the FDA strongly supports our submission,” Ruud Dobber, president of AstraZeneca’s bio-pharmaceutical business unit, said in a statement to CNN said.

“After FDA approval, we will immediately release 30 million doses in the first phase, and then another 20 million in the same month,” the statement added.

Recommendations for fully vaccinated

CDC officials said Monday that Americans who have already been fully vaccinated should visit their free family and friends without restricting it.

“In the environment that the unvaccinated people are from a single household and that all the unvaccinated people are at low risk for severe Covid-19 disease, no preventative measures are necessary. Therefore, these visits can take place indoors without mask or physical distance. , “CDi epidemiologist Tami Skoff said.

People who are fully vaccinated can visit family and friends who have not been vaccinated, but one household at a time, says CDC official

For example, fully vaccinated grandparents can visit their non-vaccinated daughter and her non-vaccinated children indoors and without masks, assuming neither of them is at higher risk for serious illnesses, Skoff said.

The recommendations only apply to people who have been fully vaccinated, Skoff said. This means that it is at least two weeks since the second dose of a two-dose vaccine series or two weeks since the single-dose Johnson & Johnson vaccine.

“There is a growing body of evidence to suggest that people who are fully vaccinated are less likely to have asymptomatic infection, and therefore less likely to transmit SARS-CoV-2 to others,” Skoff said. said.

But there are two major exceptions that require everyone to follow safety precautions: if one of the unvaccinated people is at high risk for severe Covid-19, or if there are more than two houses without vaccination that mix.

Read the CDC guidelines for people who have been fully vaccinated

A third of hospital patients have long-term effects

Researchers are also trying to understand more about the long-term aftermath of infections – and how many people may be affected.

About a third of Covid-19 patients admitted to the hospital experience long-term effects that can affect multiple organ systems, according to a comprehensive review of scientific studies published Monday in the journal Nature Medicine.

The researchers reviewed scientific literature on post-acute Covid-19 – meaning complications caused by the virus caused more than four weeks after the onset of symptoms.

Clinics are emerging across the country for what some call a potential second pandemic: Long Covid

“Long covid” effects can have an impact on more than half a dozen organ systems, including the pulmonary, hematological, cardiovascular, neuropsychiatric, renal, dermatological, gastrointestinal and endocrine systems, the studies show.

Some of the most common long-term symptoms: fatigue, shortness of breath, brain fog, tachycardia, anxiety, sleep disorders, depression and post-traumatic stress disorder.

The researchers proposed a framework for caring for these patients through multidisciplinary long-term Covid clinics and praised the work of patient advocacy groups, including the COVID Advocacy Exchange, the Body Politic and Survivor Corps, for data collection about the symptoms of patients and the coordination with researchers to help collect. more information.

CNN’s Pete Muntean, Michael Nedelman, Ryan Prior, Christopher Rios, Ben Tinker and Maggie Fox contributed to this report.

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