This is why some people will not experience any side effects from the COVID-19 vaccine

• Clinical trials and early vaccination data suggest that most individuals will not experience serious side effects after their first shot, while some have no side effects at any stage.
• Your immune system works against COVID-19, even if you have no side effects.
• Experts believe that two demographics are unlikely to experience any side effects from vaccines, and that they should not be afraid if your vaccine does not affect reactogenicity.

In preparing Americans to receive a vaccine, there has been much talk about possible side effects associated with a COVID-19 vaccine. People usually experienced one or a combination of temporary symptoms, such as fatigue, body aches, chills, mild fever or just a very sore, tender arm. And experts have also noticed increasingly rare reactions to the COVID-19 vaccine, such as a delayed rash at the injection site called ‘COVID arm’.

National health officials are taking every adverse side report seriously – a major reason why the single-dose Johnson & Johnson vaccine is currently being discontinued after six incidents of extremely rare blood clots.

With all this talk of side effects, you can build up expectations in your head to be bedridden a few days after your first or second dose. What does it mean then if your shot is largely uneven? No, nothing is wrong with you – or the dose you received, regardless of who manufactured it. Many do not realize that the side effects of vaccines are scientifically rarer than they are common. Per CDC-generated data collected from December to the end of February, only half of those vaccinated reported systemic side effects such as fever, nausea, or chills after a first dose; approximately 30% also reported no similar side effects after their second dose.

And to be clear, the most common side effect is currently understood as temporary arm pain, according to data obtained from the Centers for Disease Control and Prevention’s V-Safe system, which helps patients report any adverse reactions to a COVID-19 vaccine. It JAMA Insights report illustrates that most people would probably not experience significant reactions in general, especially not after the first dose. Arm pain, headache and chills are more common after the second dose, but only in a minority of patients.

Either way, a lack of physical response (caused by the “reactogenicity” of your body) to the COVID-19 vaccine does not mean your body is not working to build immunity to the disease, explains Stanley Martin, MD, a clinician for infectious diseases at Geisinger, a health care system in Pennsylvania.

‘Many vaccines work in different ways, but they all stimulate your immune system to some degree; if you look at reactogenicity and the side effects, it can vary depending on the vaccine, ”he says Good Housekeeping.“There is not necessarily a link between the reactogenicity side effects you experience and the success of your vaccination.”

Who is more likely to experience no side effects from vaccines?

Everyone’s immunity is different, so it may be true that two similar individuals – whether it’s age, gender, current health status – experience quite a few other side effects after vaccination … or not at all. But clinical trials on the vaccines used in the United States have suggested that certain demographics are more likely to experience side effects from reactogenicity, problems such as fatigue or headaches, while others are generally less likely.

Older individuals have historically reported fewer side effects when it comes to COVID-19 vaccines, Drs. Martin op. The younger you are, the more likely your immune response can include noticeable side effects, explains dr. Martin. CDC officials noted in clinical trials that side effects were higher for those under 55 years of age; data suggested at the time that younger people would experience more side effects than those who were older, especially after the second dose.

According to CDC data, women are more likely to experience noticeable side effects than men. Out of nearly 7,000 side effects reports in early January, 80% were submitted by women, mainly with headaches, dizziness or fatigue. Furthermore, teams behind the Modern mRNA vaccine shared that 77% of the reported side effects also came from women, according to USA Today.

Why do some people have no side effects?

This is a question that healthcare providers can not yet answer. ‘In itself there is not one specific reason; it’s a multifactorial problem, where age and gender are just two small factors related to the dilemma, “says Dr. Martin. There are many other things that have to do with the functioning of the immune system: if you are someone who has historically tended to experience side effects with vaccines, then you may be someone who is likely to experience side effects with COVID-19 as well vaccines. ”

Vaccination trials for both Pfizer and Moderna products suggested that a significant amount of people did not experience side effects at some stage, and yet it was 95% effective in preventing serious COVID-19 diseases for all involved. Whether you experienced one or four or six side effects during your vaccination process does not mean that you are less or more protected than those who have not experienced any.

“There are a large number of people who do not have the side effects produced by reactogenicity, but who are clearly protected against these vaccines,” adds dr. Martin by. Rest assured that you have done nothing wrong; your immune system works, even if you have no side effects.

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