..Victoria Guillén.
The ambient contaminants, the urban entourage and the style of life have their genetic factors that condition the state of health of the persons and conform to the exposed exposure. With the goal of deepening in the causes of the sick, this concept has acquired a mayoral protagonism. About everything, in the biomedical investigations of the last of the mano of technological advances in medicine and analysis.
Therefore, it is possible to establish causal relationships between the non-genetic factors that make up the exposure and specific pathologies. For example, the exposure to solar radiation and the development of melanoma or the concoctions that disrupt endocrine and its implication in the hormonal deregulation of individuals. These, can lead to a wide variety of pathological disorders and hormonal or metabolic bases.
The Observatory of Future Medicine has raised its head Informe Anticipando: Exposure. With the goal of giving visibility and expanding the study of the exhibit. ‘From the Instituto Roche Foundation we work together to ensure that our country is in the vanguard of innovation in health and has taken initiatives to value the medicine of the future, in the process of publishing documents like this. Y, sin duda, creemos que el exposoma va a resultar clave para alcanzar un holistic compression acerca de la aparición und desarroll de pathologis cigatas ligadas a exposions de factors non geneticos ”, asegura Federico Plaza, Vice President of the Roche Foundation.
With the aim of approaching the study of the exposoma, the Observatory of Future Medicine Medicines has developed the new Informe Anticipado: Exposoma
‘In the last years we have had a vested interest in the scientific community in identifying and defining the non-genetic factors that can have effects on health. Moreover, the form in which these factors interact with the individual. Decir, amplify the etiologic knowledge in the camp of the exposómica ”, signals the coordinator of the information, the Dr Nicolás Olea, optional specialist at the Clinical Hospital of Granada.
Asimismo, el Dr. Olea apunta: “This interest is justified by the results of projects such as the Global Burden of Disease study. This study has determined that millions of deaths have been associated exclusively with air, water and soil contamination. Es decir, el 16% de las muertes a nivel mundial. These data demonstrate the relevance of identifying the ambient determinants of the pathways. With the goal of improving the health of the people. These factors can intervene in the development of many different pathologies of high prevalence. For this reason, his study results in the development of preventive actions, diagnostics and individualized therapies in the field of Personalized Medicine of Precision”.
According to Martin de Dios, the study of the exhibit will be fundamental in the design of preventive, diagnostic and therapeutic actions in the medicine of the future
In this sense, Consuelo Martín de Dios, managing director of the Instituto Roche Foundation, added that “the study of the exposoma will be fundamental in the design of preventive, diagnostic and therapeutic actions in the medicine of the future. In addition, of a herramienta onontbeerlik in the policies of public health, together with the advancement in new technologies, the development of human biomonitorization and the creation of new herramientas and potential data bases ”. Thanks to the multitude of emerging technologies, it has opened up to the study of the implications of different exhibits. Asimismo, it is possible to identify biomarkers of risk to develop some pathological associations associated with exhibited species. Also, design pathology prevention initiatives concrete or form recommended health habits for population groups and individual form.
In the specific case of SARS-CoV-2, a high level of variability between patients in terms of pregnancy, Dr. Olea considers that a key factor to determine the cause of this variability is the exposure itself. That is, the conjunction of all the exposures to the life of an individual. It is said, from the ambient toxins, to the pharmacological treatments, following the style of life or the diet.
El Dr. Olea considers that a key factor for determining the variability of SARS-CoV-2 variability is the same in the same
‘If exposure to ambient contaminants has been described, as well as life style choices, pueden may affect the expression of some of the proteins that act as a receptor of the virus and consequently may contribute to the severity of the infection.”, Señala el coordinator del Informe Anticipando.
‘YOUA recent report indicates that higher levels of airborne contamination may be a factor contributing to the increase in mortality rates among patients with COVID-19. On the other hand, the diet and style of living can also influence the determination of resilience. As such, susceptibility to more serious consequences has triggered the SARS-CoV-2 infection. Ultimately, it is suggested that the racial and ethnic differences that determine different types of metabolic and cardiovascular transgenic pathogens may contribute to the gene / environment interactions that conditionwith the susceptibility to COVID-19”.
Exposum Future Retos
Taking into account the hallucinations, it appears that the study of the exhibit is contributing to the knowledge of the origin of many diseases. Sondeverbod, pesar de los advances en los ultimos años, su studio todavía resultta muy complex. Some of the aspects of difficulty in analyzing its diversity and the amount of molecules involved are the agents it composes. Moreover, from the hecho of which the exhibit is dynamic, it varies from time to time
The study of the exhibition requires a multidisciplinary approach, supported by the knowledge of disciplines such as toxicology, epidemiology and the ancient sciences, among others
For this reason, the exposoma study board should follow a multidisciplinary approach. It is supported, supported and complemented by the knowledge of other disciplines, such as toxicology, epidemiology, clinical medicine, omniscient sciences and data sciences, among others.
Según señala el Dr. Olea: “In the future, the exposure together with the genome should be studied at the end to obtain a holistic vision of the pathologies. You will be able to open new doors to the translation and clinical practice derived from the study of the exhibit, for which collaboration will be necessary between the investigators, the health care professionals and the administration. However, the future of the exhibition and its translation into the practice and translation of sanitary policies do not depend solely on scientific interests, the possibilities of application and innovation, so that it will be necessary to count on funding and establishment”, Conclusion.