Scientists from the Continuing Netherlands use the traits that train the nurses as the triple negative cancer, nursed with a poor prognosis between patients debilitating to tumor aggression.
Belinda Z. Burgos González
Agencia Latina de Noticias Medicina y Salud Pública
And that’s what Dra’s labs do. Esther Peterson and dr. Josué Pérez of the Cancer Research Center, will evaluate the molecular mechanisms and modes of genetic expression that go beyond the aggression of this type of tumor, and that affect young women in pregnancy.
“Triple Negative” is the term used to describe the tumors that have ER-negative, PR-negative, and HER2-negative receptors. These are not responding to the hormonal therapy or the direct therapies-HER2.
This study is performed on cellular breastfeeding models in vitro.
“Inflammatory cancer can be found in other subtypes that have an estrogen expression and that have a total implication in the growth factor that also causes triple negative tumors, the important one is what it is at the moment is that the triple negative tends to direct therapies with the end of incrementing one more treatment, ”explained Dr. Peterson.
“There are therapies that first can control the patient and increase the patient’s survival. Previously, he studied molecules in vitro, his cells that make patients sick with inflammatory cancer, because we would like to increase the burden and that we should know if the cells with estrogen and then the aggressive aggressive agents.
On the other hand, Dr. Pérez sostuvo que también se busco conos cellular cambios que ocurren en est enfermedad.
“It is also important to know that receptors are involved in estrogen therapy, as it tends to involve biology in the agents responsible for developing the migration aggression genotypes and which genes can associate with these cellular processes,” he said. investigator.
Furthermore, it indicates that the team is looking into the possibility of sequencing the genetics of the patient in the manner in which the expression processes that drive the development of the affection may be performed.
“The genetic part of some way of accessing the primary patient has some condition with the condition and in this way we can know the transcription process that we are and so we can follow the gene of the person,” the doctor said.
However, although this investigation is taking place in a timely manner, both investigators will ensure that as soon as the finals of this year and when the ambient proposition exists, the experimental models with ratios will exist.
“We are confirming that we are dealing with estrogen cells that have a change in the genotype, so we want to have mayor proliferation and cellular migration in experiments. We found that there are cambios in the quinas (type of enzyme that modifies other molecules, which can explain the aggression that is in the case of senile inflammation.) The doctor concluded.
Between the 13th and 15th century, some of the poorest women’s develop a triple negative mother cancer.