Our country will soon have a new one Nobel Prize although in this occasion the elders are bound.
This is the Chilean scientist Ricardo Maccioni submit nominations to Nobel Prize in Medicine 2021 for its contributions to the knowledge of the Alzheimer’s.
The Doctor of Science is Academic at the University of Chile and will lead the International Center for Biomedicine for over 30 years, and is dedicated to finding the cure for this neurodegenerative disorder.
The connected researcher is given the time to converse with BioBioChile of different themes, obviously the pandemic on the podium will be present. It seems that it has changed in a difficult period for the whole world, recognizing that for them and their team they have productive times.
“It has been a long time since we saw scientific publications during the pandemic, which is a record for publishing high-impact scientific papers. Want to know that he has a very coordinated work during the pandemic. I’ve been working in my office since the 7th of the month, and I have 76 more reviews to complete ”, comenzó señalando.
The legacy of the first vacancies in our country means that the Chilean scientist will be the future of an optimistic manner. “A pandemic is something that is cured by grace, but pandemics have a habit in humanity in many opportunities,” she said.
“The theme is what makes the future, in the midst of the awakening of the people, there is the possibility of it advancing the advancement of the sick. “As long as you have a car in the water and you’re freaking and freaking out, you’ve been abusive and you’ve been in control,” he said.
In this sense, the Doctor Maccioni understands that the recommendation is vacant. “There are all the facilities for the people to access the caravan. He visited a poco de confusión en las personas todavía ”, añade.
“Do not use mascarillas without any justification. If you use and maintain social distance, that’s clear. I’m excited to see you at the supermarkets in the agglomerated people, so I can not be. Now, obviously there is a vacancy policy, it has inevitably been proven that it works ”, continues.
Respectively, the investigator said that “all the vacancies are functioning”, referring to the case of the child who was under the control of the inoculation as well as the viral infection.
“All these great advances he has on the vacancies. Geen hooi ninguna razón médica para pensar que las vacunas geen sirven. It is unjustified that vacancies can produce autism in children. There are some ways in which salons are part of it and do not have any scientific help ”, expressly.
“El gobierno toma las medidas correctas. The child is the one who has some manner of proper manners. If you say that in supermarkets there is an affair of people who can enter, no one can be there. It can not be said that, because it is verona, toda de gente desemboque en las playa, que hayan miles de persona en een pequeña sin ningun typo de control ”, argumenta.
‘Hey, tener mayor, conciencia. It is not a goberno theme or ordinance. Quizas habría que ser un poco más firms como in paises como New Zealand, by practically extinguishing the virus. “It’s a little bit more like Chile, but it’s comparable, it’s just like ours,” he said.
Since joven the Doctor Maccioni is interested in studying the Alzheimer’s, “When nothing happens to my very little one. It’s a topic that interests me so much ”, explains.
The University of Chile is entitled to conduct its superior studies in biochemistry at the University of Chile. Centro de Ciencias de la Salud de la Universidad de Colorado, Estados Unidos.
Among other important advances, the scientist will lead the development of a test that will allow him to diagnose the Alzheimer’s with a song sample.
“It is an invasive test that is called Alz Tau“that in one of these months it will be available so that the Chilean population, from Arica to Punta Arenas, can be reached,” he said. All are based on the detection of a key molecule in the development cycle: the protein TAU.
Specifically, it is a system that consists of two kits. The first is to prepare the plaque protein, while the second kit is to make the analysis that indicates the value that these variants of the TAU protein have.
As such, this scientific proposal is positioned as an alternative only in the world that with a state-of-the-art technology allows tenacious and predictive information, only as diagnostic as temporary detention, up to 10 years of antecedent.
The test is based on the presence of high or low molecular weight of this protein, all from the lack of algorithms. In this sense, the biomarker consists of calculating species of high molecular weight and low molecular weight of the TLU protein, which indicates that in Alzheimer’s cases the species of the alto dominates, and there is a correlation with about 90%.
Currently the biochemistry is underway in its research work. Will be published on the magazine Journal of Alzheimer’s Disease his new studio called New frontiers in Alzheimer’s prevention, diagnosis and treatment, which proposes an integrated approach that includes preventive and pharmacological factors for the future control of illness.
The academic has its own expectant abilities in that it mediates a multitarget therapeutic approach, which may have different objectives, can control the illness.
‘Pero not with a simple drug, so lo he dicho muchas veces. If you treat Alzheimer’s with a drug against some cerebral enzyme, not the vase to check anything, because it is an event within the decade of events that are uncorrected in the cerebro alterado with the nurse. Entries can control one part pero all. The idea is to control different levels ”, argues.
¿A third Nobel Chilean?
The Doctor Maccioni acknowledges that any scientist is experimenting with a large allegory for being nominated for a Nobel Prize. “In the background, it is a reconciliation to the years of work. The scientists have very little knowledge, but if they read it, they are logically welcome, ”he said.
“A series of tremendous honors for me and my research team, because it does not work alone. And for another lady, a series honoring Chile, because there is a unique event for our country, which has never won a Nobel Prize in Medicine, never has a premium in tenacious duration. It is located in Chile in the global sphere, in an important position.
Finally, send a message to those young people who are beginning in the world of the elderly. “First of all, let’s assume that making science in Chile is not easy, that we should redress the efforts with respect to what we have made scientists in countries such as the United States,” he said. “He who is reticent, it is said, to have the very strength to be removed from the offices,” he added.
Además, empathize with the importance of perseverance and hard work. ‘Yo he llegado a esto trabajando 20 horas diarias durante mucho tiempo. There are 76 years and I am working for 20 hours 16 hours. It’s legally related to my vacations, but I’m staying at the canyon, working ”, indicated.
So much so, he explained that he had to be honest and think big. “No hay that is bad. The projects can be realized. All those who were trained in my laboratory had this cell ”, conclusion.