A comparative approach that covers human medicine, veterinary medicine and New Year’s Eve can allow us to complete in more complete ways the general comparisons necessary to resolve the COVID-19 public health crisis and prepare for future pandemics”, Manifiestan a group of scientists from the Department of Microbiology and Immunology and the Center Felud Felina of the Faculty of Veterinary Medicine of the University of Cornell (EEUU), in a recently published article.
In the context of the COVID-19 pandemic in the pipeline, the authors signal that comparative medicine can be a powerful tool to help refine the coronavirus pathophysiology, the efficacy of vaccines and pharmaceutical interventions. With feline infectious peritonitis (FIP), in particular, it has been recognized that coronaviruses are important causes of infestation in animal species for many decades, and in some cases are associated with the enigmatic results now known as COVID-19 humanos. “The cats and other animals have also been affected by the presence of respiratory syndrome and severe coronavirus 2 (SARS-CoV-2),” he said.
Asimismo, explanatory que Endothelial and vasculitis are established as a systemic system component caused by SARS-CoV-2, including in others that develop multisystemic inflammatory syndrome (MIS-C). A series of cases also described an adult multisystemic inflammatory syndrome (MIS-A), which included a variety of extrapulmonary disease manifestations. By analogy, el felon coronavirus (FCoV) is well known for its ability to cause FIP, which is also a multisystem inflammatory inflammation of the guts, although classically defined as effusive (accumulation of liquid in any corporeal cavity) or no effusive (development of granulomatous lesions and piogranulomatous lesions in all corporeal systems). “The only multisystemic signs are known to be most recently linked to the infection by FCoV. The protein of the spider contributes to the cellular tropism of the virus. The major antidepressant (ADE) dependent is considered a possible mechanism contributing to the FIP development. The ADE has not considered a major mechanism that stimulates the pathology of COVID -19 and “SARS-CoV-2 replication in macrophages appears limited; without embarrassment, it will be open and resolved issues”.
Also note that the holes are vatbaar vir to SARS-CoV-2, so experimentally as in the community. The feline infections can be quite common, but the clinical signs appear to consist only of live respiratory signs. Another group of susceptible animals are the mustaches, including the hurones and the visons. In particular, it has observed the spread of the virus between the vision and the human tissues. In many cases, the vision develops a severe interstitial neuron and then alveolar diffuse with systemic signs, such as “hepatic lipidosis, chronic nephritis, sepsis, dystocia and urolithiasis”. The experimental challenge of the species of domestically related strains has not produced serious signs, and the suones hurelen respond like holes. ‘Just as with the holes, both the visons like the albergan hurricanes on the coronavirus propositions, and the hurricanes must have a systemic result opmerklik which consists of a P similar, but with less vasculitis. The impact of coinfection with human and animal coronavirus in this context of susceptible species, including clinical presentation or viral recombination, is currently not clear, ”he said.
On the other hand, the authors subdivided by the Term “Una Medicina” by Rudolf Virchow in the finals of the XIX sailing y sigue siendo una piedra hoekig de la pathología del siglo XXI. “Virchow associates itself better with the” triad “of the same number that includes the components of venous thrombosis, including venous stasis, activation of sanguine coagulation, and endothelial donation. This trio contributes to the multisystem signals as well as COVID-19 as well as FIP. ‘A Medicine “also constitutes the basis of the trio of people, animals and the middle environment, which has been widely expressed as” A sola salud “. The ambient medium is key to the SARS-CoV-2 propagation events, both local (p. Ej., In viscose grenades) or global (p. Ej., In murciélagos and its species of intermediate species) “.
Definitely, just as with Virchow in sail XIX, the experts signal that “today we will examine the coronavirus as much as humans as animals using a comparative approach that eliminates human medicine, veterinary medicine and life, incorporating the two distinct triads that inspired Virchow. It is possible to establish in more complete ways the general comparisons necessary to resolve the COVID-19 public health crisis and to prepare for future pandemics ”.
The intersection of the One Health triad with the Virchow triad to coronavirus infection.