(CNN Español) – The vaccine against coronavirus and its variants is a topic of actual scientific study. Investigators from Israel are analyzing the Pfizer / BioNTech antigen against the variants identified in the United Kingdom and South Africa.
In this episode, the doctor, Elmer Huerta, no longer examined the results of the examination.
You can watch this episode on Spotify or your podcast platform to learn or continue the transcript.
Hello, soy, dr. Elmer Huerta and this is his diary dose of information about the new coronavirus. Information that we hope will be useful to take care of his health and that of his family.
We will see a pre-publication from the Tel Aviv University in Israel, which informs that people completely vaccinated with the Pfizer / BioNTech vaccine are infected in a disproportionate manner with the variants detected in the first time in South Africa and the United Kingdom.
Coronavirus variants and their impact on vacancies
The possibility that the new coronavirus variants could impact the effectiveness of the vacancies, diagnostic tests and including the treatment of large monoclonal anticoagulants, as administered by the United States Medicines and Food Administration (FDA) the manufacturers of their products in order to adapt to the new variants of the virus.
As proof that the first generation vacancies that are being used will be less effective against the newer variants, an internet pre-publication on April 9th describes a study that demonstrates that the persons who received the vaccine from Pfizerier / BioNT frequency of infection by variants B.1.1.7 found in the United Kingdom and B.1.351 found in South Africa.
The Israeli investigation
To empezar, the investigators clarify that the studies he has been listening to in order to determine the effectiveness of the vacancies versus the variants his experimental studies in the laboratory, by which ten restrictions can be generalized to real life.
To improve this limitation and to ensure that the vaccine protects one of the variants in real life, investigators design a study to determine whether to receive the Pfizer / BioNTech vaccine and the covid-19 vaccine drop-out rate in comparison with individuals have no vacancy- most probabilities of developing infections with some of the variants detected by first time in South Africa and the United Kingdom.
How will we study the cases?
To do this, study the cases of people who receive a vaccine in the Clalit health system in Israel, a public health insurance organization that includes 53% of the population, and separate all the people who become infected with the new coronavirus by at least one week after the second dose, and so much so that he was completely evacuated; all those who infect at least once a week after the first dose, it is said that they are partially paralyzed.
In total there are 149 cases of people being infected completely vacant, and they are compared with 149 cases of people who also became infected, but could not receive the vaccine.
In the same way, we identify 247 people who are infected in various vacancies, and compare them with 247 people who are also infected, but have not received the vaccine.
And the reason for comparing vacancies and vacancies in both groups, is to have different differences in the type of virus that infects both groups.
To that end, we need to have a complete genomic sequencing of all viruses transmitted in the study persons, and determine which variant is the one that causes the most infections and in which group.
Results: less effective ante variants
The results of the demonstration study that -a comparison with the vacancies- the 149 people completely vacancies are infected in a disproportionate manner with the varied South African. The ratio of 8 to 1, that is, 8 infected in the vacancies, by one in the group of the vacancies.
For its part — in comparison with the vacancies — the 247 persons in vacant lots are infected in a disproportionate manner with the British variant. The ratio was 26 to 10, that is, 26 infected in vacancies, per 10 in vacancies.
Investigators conclude that there is a reduction in the vaccine efficacy against both variants of the new coronavirus, which are different in dose and time conditions. Agregan requires more research to find out if there are any potential limitations affecting the results.
Are there new vacancies before the variants?
Respectively, the majority of laboratories are working on the second generation of vacancies, which cover the new variants, and the FDA has recommended that now — and with cargo to discuss the details in the future — the new vacancies no. tengan que pasar par los largos estudios de phase 1, 2 y 3, sino que demuestren la capacidad que tienen de estular de defense system in studios in persona den no hayan sido vacantadas previamente.
For the last time. In terms of contraception, the researchers say that a massive combination of the dose with the dose, unite in the use of mascarillas and social distance would greatly contain the propagation of the variants, especially of the South African, a moment in South Africa in this country.
There is no doubt that — having read the second generation vacancies — these recommendations can be applied to all lands that are affected by the new variants.
Do you have any questions about coronavirus?
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