Pfizer, AstraZeneca, Sinovac … What are their vacancies against Covid-19?

Since the start of the Covid-19 pandemic, the world has been searching for the feasible alternative to control the contagious and eradicating lethal disease that has affected millions of lives in more than one year.

The physical distance and the mascarillas he used, but he did not have a sufficient palliative care.

The law of science is to reduce the contagios and combat this coronavirus by means of vacancies, which the various countries he managed to administer and the Dominican Republic had no specific power to initiate, only the Governor confirmed that the month of February .

As of December 2020, there have been more than 200 vacancies in disarray, of which 7 are currently circulating around the world, although they are used for emergencies.

The Dominican Republic will receive the vacancies of Pfizer, AstraZeneca and Sinovac, which was last announced by President Luis Abinader in the case. What are their inoculations?

Pfizer-BioNTech

The BNT162b2 vacancy from Pfizer and BioNTech has 95% efficiency, being the mayor’s percentage of more than 30 vacancies worldwide.

The clinical trials have completed Phase 3, and are being used in person for 16 years or more. Without embarrassment, he does not recommend his application to people who have reacted to allergies to polyethylene glycol (PEG) and polysorbate.

If you need a dose dose, with 21 days between each, if the patient has a severe allergic reaction or an immediate allergic reaction with the first dose, do not receive the second injection.

Debe est refrigerado a -70º, y puede permanecer cinco días congelada.

It is authorized by the United States, the United Kingdom, the European Union, the World Health Organization and other countries.

Scalphries, cancer and cabbage pain are some of the secondary effects that appear within the 7 days after being vaccinated.

With this pharmaceutical, the Dominican government has established an agreement to secure 7.9 million doses of the BNT162b2 vaccine.

The agreement was signed by the Minister of Public Health, Dr. Plutarco Arias, representing the Dominican Republic.

Prior to this agreement, President Luis Abinader announced that he would also return in January during the course of this month, which will receive a 25-mile dose of the vaccine manufactured by the pharmaceutical company Pfizer, without embarrassment.

Pfizer and other pharmaceuticals have recently withdrawn with the entry of the vacancies in contracted countries.

Modern (United States)

With 94.1% efficacy and Phase 3 of completed clinical trials, the vaccine developed by Moderna Pharmaceuticals is the second with Mayor efficiencies in the world, as well as the second to be approved by the European Agency of Medicines (EMA).

This vacancy requires a 30 day break, but can support up to six months refrigerated at -20 degrees Celsius.

To use it efficiently, you can create applications with a difference of 28 days between each. However, in the end of the year, the pharmaceuticals announce that the efficacy to generate anticonvulsants against the South African version is less than for the original virus, because it works in a new vaccine that can probably increase the actual dose.

United States, Canada, United Kingdom, Israel, Switzerland and countries conforming to the European Union are some of the countries in which the modern state of emergency is applied, developed with the United States National Institutes of Health and authorized by the World Health Organization Hello.

In addition, the United States Medicines and Food Administration (FDA) authorizes the vaccine against the modern-day covid-19 for emergency use in this country.

Sputnik V

The Russian Sputnik V vaccine, developed by the Gamaleya Institute of Investigation in Russia, is one of the world’s top 50 vaccines with a 90% higher efficiency.

Although the products produced by Johnson & Johnson and AstraZeneca, the Sputnik V is a viral vector, it differs in that it uses a different adenovirus in each dose.

According to Gamaleya’s investigations into the efficiency of Covid-19 in this area, which is the number one of the Soviet space’s primary satellites, it’s 91.6%, to demonstrate a high level of immunogenicity and safety during phase III clinical trials.

Contrary to what AstraZeneca screen experts say, the vaccination center ensures that the effectiveness of the vaccine for advanced age people is 91.8% and does not differ statistically from the group of people aged 18 to 60 years.

This vaccine requires doses, with three weeks of difference between each.

“With the aim of securing a longer-lasting immunoassay, Russian scientists have unveiled the new idea of ​​using different types of adenoviral vectors (rAd26 and rAd5) for the first and second dose of the vaccine, thus reinforcing the effect of the immunizer”, of the vacuna.

En cuanto al almacenamiento, se debe cool in a -20 degree Celsius.

Sputnik V has approximately 15 registered countries, including Russia, Venezuela, Argentina, Bolivia, Belarus, Serbia and Argelia.

Oxford-AstraZeneca

The Dominican Republic and the Anglo-Swedish company AstraZeneca have signed a contract for the acquisition of 10 million doses of the vaccine against Covid-19.

The technology used in AstraZeneca’s vacancies is a viral vector, that is, a non-invasive virus that is created to contain the gene for the SARS-CoV-2 protein protein, which prepares the immune system to attack the SARS-CoV-2 virus. if luego infecta el cuerpo.

The pharmaceutical informs of an efficiency of more than 70%. However, according to the data presented by the EMA, a 60% increase in demonstration is demonstrated in clinical trials.

The Covid-19 car AstraZeneca is not currently recommended for use in schools; while 55 year old adults, recently, experts from the OMS express their displeasure with regard to efficiencies in the mayor’s edad and against the South African variant of the virus.

Developed with the University of Oxford, AstraZeneca’s application is authorized in approximately 50 countries, including the United Kingdom, India, Morocco, the European Union and various countries of Latin America.

For emergency use, the vacuum should be refrigerated to a temperature of between 2 and 8 degrees Celsius for a period of less than six months.

Sinofarm

The technology of this vaccine consists of inactive virus. The SARS-CoV-2 virus is converted inert to traps by a process that preserves the structure of the virus in order to be able to reproduce, while generating an immune response in the organism.

Developed by the Chinese state pharmaceutical company Sinopharm and the Institute of Biological Products of Beijing, the vaccine culminates in the ultimate phase of clinical trials and has an efficacy rate of 79%. The laboratory has approved the regulator’s approval for the injection, which will be converted into China’s first vaccine approved for use by the General Public.

Its use is authorized in China and in some other countries, such as Hungary, Serbia, United Arab Emirates, Bahrain, Seychelles, Egypt, Laos and Morocco. The dose required is two, with three weeks between each.

Although AstraZeneca, the rating is 2 to 8 degrees Celsius.

Johnson & Johnson

Johnson & Johnson is a company known in the country for distributing baby care products, in addition to its manufacturers of medical devices and pharmaceuticals, being one of the most recent vaccines against Covid-19.

The technology used is a viral vector, the mix of AstraZeneca and Sputnik V.

According to periodic reports, the vaccine showed an efficacy of 66% with a dose of 85% at the time of prevention of serious diseases.

However, data from most of the data shows that there are more effective tests in the United States (72%) than in South Africa (57%), where there is a distinct virus that is predominant.

The FDA has applied for authorization for the use of this vaccine, and the company informs that the February finals will issue its dictation while studying the data of the clinical trials.

Some medicines for this medicine are a single dose and do not require special treatment. Además, you can stay up to 20 degrees Celsius, and three months refrigerated between 2 and 8 degrees Celsius.

CoronaVac

CoronaVac is a vaccine against COVID-19 developed by the Chinese pharmaceutical company Sinovac Biotech, a vaccine specialized in vaccines, among them for hepatitis A and B, stationary influenza, porcine flu and avian flu.

The efficacy of this inoculation, according to Sinovac, is an increase of 50% in the prevention of contagion and 80% in cases that require hospitalization. These are the results of the trials and clinical trials conducted in Brazil and Indonesia during Phase 3.

Coronavac converts to early February vaccines against the coronavirus authorized by China and is used in Indonesia, Brazil and Turkey.

According to France24, the CoronaVac requires doses to supplement with its effectiveness and require a refrigeration rate of between 2 and 8 degrees Celsius.

On Thursday, President Luis Abinader announced the acquisition of 768,000 new Sinovac vacancies.

The mandate does not specify the cost of the Dominican Republic.

Discount Efficacy

Other vacancies in desarrollo son la CureVac (Germany / EU) by ARN messenger and Novavax, developed in the United States with recombinant pickle protein, but the work efficiency is discounted.

In addition, the pharmaceutical company Novavax announced the final results of its 89.8% efficacy clinical trials during its Reino Unido variant.

In equal form, there is inoculation Sanofi / GSK (France and United Kingdom), developed with recombinant protein. In February announcements were published in media that revealed a phase 2 decaying assay, the companies are trying a different antigen formulation and are now in production this year.

Sepa Más

Other vacancies

In addition to the existing exits, other vacancies such as those of the Indian company Bharat Biotech, developed and authorized in their country of origin, phase 3 clinical trials have no conclusions. Treated by the pharmacists Covishield and Covaxin.

ARNm Technology

The most effective vacancies are among the competent organizations and entities held in common with the development of ARN messaging technology (ARNm).

This form consists in that the drug teaches our cells to produce a protein that stimulates an immune response within our organism.

‘N Su portaalweb, the Centers for the Control and Prevention of Diseases (CDC), explaining that this immune response, which produces anti-cancer, is what protects us from infections if the real virus enters our organisms.

Please note that these vacancies can provoke COVID-19 and also contain the live virus that causes COVID-19. Asimismo, does not affect our DNA and does not interact with it in any form.

.Source