Specialists in transplantation of all Spanish and known first hand during the ‘IX Reunion Detecta 2021‘, who organized Astellas Pharma, with the agreement of the Spanish Society of Transplant (SET), the last Updates on the antiquated media release (AMR), as well as the paper that used to play the molecular biology techniques to be more precise at the time of making the humorous diagnosis and log a much more personalized approach to the patient that is being transplanted or requiring a transplant.
El rechazo humorit is the first cause of loss of the injection and will affect approximately one 25% or 30% of patients, según Daniel Serón, Coordinator of the Detective Reunion and Chief of Neurology Service of the Universitario Vall d ‘Hebrón de Barcelona Hospital. This case of inclusion includes “patients who need a second transplant and who, as he was exposed to antigens from his first donor, has a mayor risk of having a humorous rash”.
To anticipate this situation, the analysts have now analyzed the similarity of those between donor and receptor mediating the determination of any antigens that indicate if there is no compatibility. Sondeverbod, a technique based on epitopes constituted by a group of continuous amino acids in the sequence of protein, the conformational (eplets) powder can have a great advantage in preventing humoral mediation through the addition of a personalized treatment for each patient.
“During the last years he developed techniques that allow him to quantify very well his differences in molecular levels, is not one of the antigens, it has no antigen, and it is associated with the risk of having a humorous retreat ”, explained the specialist. ‘This is an important point because it has been shown that only the predisposition is to sell the transplant, so that it has an idea to adjust the immunosuppression treatment according to the separation between donor and receptor ”.
Currently, transplant persons receive a live immunosuppressant treatment what proposal is to avoid organ failure, by abandoning this therapy or failing to adequately provoke the appearance of anti-HLA anticoagulants and, for that matter, the loss of injected. By the way that the application of apples supports an optimization of the use of tacrolimus, the treatment is that all transplant patients receive to avoid the transplantation of the organ, by means of a much more personalized treatment than necessary.
‘Takrolimus following the basic plan to prevent transplant patients.4 “The tacrolimus car key question is how we can optimize its use, we can add the tacrolimus amount that a personalized patient needs and this technique allows precisely to do this abortion”, affirmed the Dr.
Advances in the field of digitization
The statements of the IX Reunion are given by national experts, as well as by international specialists, such as Michael Mengel of the University of Alberta (Canada) and Cinthia B. Drachenberg, University of Maryland, Baltimore, (EE.UU.).
The experts also analyzed the implications that tend in the immediate future the advances in the diagnosis of humorous, debit and herramientas that much more accurate. In this sense, Seron has had a tremendous advance on image analysis systems based on techniques such as artificial intelligence and neural networks, among others. “We are undergoing complete digital transformation of pathological anatomy laboratories. I would like the biopsies to be photographed and displayed on computers. This change allows you to get automated information and access all those data that are monotonous and repetitive, but also know and quantify if you have less than one lesion ”.
In this sense, the coordinator of the Reunion Detecta has asserted that in the camp of pathological anatomy it is to produce in five or six very important changes of the mano of the digitization and its applicability. These techniques exist and are encapsulated in the process of translating the basic investigation into the clinical application.
Other messages sent during this meeting were related to the memory that holds the memory cells. “These are the cells or linocuts that one time he recognized an antigen, has a robust and fast-moving munitions response that also estimates the B cells that are transformed and are the ones that produce the anti-body“With these memories, memory cells are important for cellular and humorous relationships,” Serón explained.
On the other hand, the transplant specialist has announced the lack of evidence that is currently related to the treatment of patients referred to rechazo humorous chronicle. “Being healthy is something new, but it is in the clinical trial phase and today it does not know if it will add a lead or not. These new treatment directives, or rather modular anticursors, have mechanisms that allow them to modify the immune response, but to no avail. ”
The 9ª edition of Detecta
During the meeting, the experts pointed out the different advances that are needed to apply in clinical aspects and that in the near future we should be able to a much more integral and personalized approach to the patient. For this, the program planted a corridor for the different ambitions of the nurse.
In the month of Pathology, in accordance with Cinthia B. Drachenberg, of the University of Maryland and EE.UU.); el Michael Mengel, from the University of Alberta in Canada; y Francisco O’Valle, of the University of Granada, he exhibited the current situation, advances and molecular biology techniques to be more precise in the timing of the diagnosis of humorous recovery, as well as the implications that digitalization has in the future.
For its part, David San Segundo, del Hospecaal Marqués de Valdecilla y Luis Guirado, of the Puigvert Foundation, has addressed the theoretical foundations of apples and its clinical utility in the prognosis and individualization of patient care in a single month on immunosuppression.
Posteriorly, with the aim of making an update of papel de la caracterización de anticuerpos for the prognosis of the humorous recurrence and the effect that these are antiquated in the hygiene and the reunion, a month on immunology was counted with the participation of Dolores Redondo, del Hospitaal del Mar y Jordi Colmenero, del Hospital Hospital. Además, Oriol Bestard, of Bellvitge Hospital, profound in the role of designing the memory cells of the cellular and cellular memory.
Finally, I wanted to have a month around artificial intelligence in the que Ramón López de Mantaras explained at what point it is currently and what is possible to do in the current with this technology in the practice of clinical diarrhea.