New evidence that Covid-19 antibodies reduce the risk of re-infection

A health worker takes a drop of blood for a Covid-19 antibody test at the Diagnostic and Wellness Center in Torrance, California on May 5, 2020.
A health worker takes a drop of blood for a Covid-19 antibody test at the Diagnostic and Wellness Center in Torrance, California, on May 5, 2020. Valerie Macon / AFP / Getty Images

According to a study published in the journal JAMA Internal Medicine on Wednesday, you can significantly lower the antibodies of Covid-19 against a previous infection.

“The results of the study are basically a tenfold reduction, but I want to reserve against it. In other words, it can be an overestimation of the reduction, it can be an underestimation of the reduction,” said Dr. , chief deputy director of the National Cancer Institute, who was an author of the study.

“For me, the big message is: there is a reduction,” he said. “The most important takeaway is that being antibody positive after natural infection is accompanied by partial protection against a new infection.”

How they did the study: The researchers examined data on more than 3.2 million people in the United States who completed an antibody test between January and August last year.

Among those tested, 11.6% tested positive for Covid-19 antibodies and 88.3% negative.

  • 0.3% of those with antibodies tested positive for Covid-19 infection later than 90 days.
  • 3% of those without antibodies tested positive for reinfection during the same period.

But more research is needed to determine a causal link, how long protection against antibodies can last and the risk of reinfection against a variant.

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