A study found that a low-calorie diet and a moderate exercise program can drastically improve the survival outcomes for children and adolescents diagnosed with the most common infantile cancer – acute leukemia, according to UCL.
Investigators are looking to find patients who reduce their calorie intake by 10% or more and have adopted a moderately moderate exercise program after diagnosing it, on average, 70% less likely to have persistent leukemia than those those who do not follow the diet and diet regimen.
“We try a very healthy diet because it was the first time we used it, and the first treatment is difficult for patients and families”, says the study’s principal author, Steven Mittelman, Head of Pediatric Endocrinology at UCLA Mattel Children’s Hospital and member of the UCLA Jonsson Comprehensive Cancer Center. “However, including these changes in diet and exercise, the intervention was extremely effective in reducing the likelihood of detecting leukemia in the ocean.”
Mittleman says that the investigators hope that the intervention will lead to better results, but there will be no idea that a series will be effective.
“Actually, we can add more chemotherapy drugs to the intensive treatment phase, but this is an intervention that is unlikely to have negative or secondary effects. Therefore, we hope that this includes reducing the toxicities caused by chemotherapy, ”he said.
In a clinical trial at CHLA, investigators working with dietitians and physiotherapists to create personalized interventions of 28 days for 40 days between the ages of 10 and 21 that were recently diagnosed with acute lymphoblastic leukemia.
The interventions were designed to reduce the caloric intake of the participants by a minimum of 10% to reduce the amount of fat gained by mass gain, while the physical activity component includes an objective level of 200 minutes per week of moderate ownership.
Mark the first attempt to try a diet intervention and exercise to improve the results of the treatment of an infantile cancer, says the director investigator and principal author Dr. Etan Orgel, director of the Medical Supportive Attention Service at the CHLA’s Institute of Cancer and Injuries, called it “an emotional conceptual test that could have great implications for other cancers, too.”
The focal point is being tested for continuation in a multi-centrifugal high-speed drive that will launch the finals this year, investigators said.
The other authors of the studio included Jiyoon Kim and Gang Li from UCLA; Celia Framson, Rubi Buxton, David Freyer and Matthew Oberley of CHLA, Weili Sun of City of Hope, Jonathan Tucci of the Vanderbilt University Medical Center and Christina Dieli-Conwright of the Dana-Farber Cancer Institute in Boston.
The results of the study were published in the Journal of Hematology of the American Society.