Janssen’s vacancy, funded by Johnson & Johnson, demonstrated mayor’s efficacy in the application of a single dose, agreed with the results of safety and immunization profiles published by the company.
Efficacy results with a single super dose on those that require doses. In addition, it is known that the antigen can be preserved for three months at temperatures of 2 to 8 degrees Celsius.
With this publication, the company listens to solicit the emergence service in Mexico, where clinical studies are currently taking place, as well as other countries. However, these bodies will be analyzed by bodies such as the Federal Commission for the Protection of Sanitary (Cofepris) or the Food and Drug Administration (FDA) in the United States.
Agreed with the publication in die New England Journal of Medicine, is detectaron anticuerpos neutralizantes antiviral type salvage en 90 per cent of participants the day 29 after the first dose of vaccine.
The antibodies that neutralize its proteins that are active in defending against the invasive virus organism, the cells increase the price by protection in day 57, independently of the dose of vaccine or the edad group. In addition, the stable is stable at least 71 days.
On the 14th day, T CD4 cell responses were detected at 83 per cent of participants, that is, from the white globules that fight infections and develop an important paper in the humanitarian system.
The responses of the T CD8 + cells are robust in general. Linfocytos are activated by cells that are infected with viruses and protected by the antigen.
Pes al amplio margin de respuesta, los eventes adversos o secundarios se se presenter de burgemeester frecuencia fueron la fatiga, el cabeza dolor, mialgia y malestar en el lugar de la injection; being the most frequent the fever. Prohibition of probes, these effective fueron less common in those who receive the low dose of the vaccine, which in those receiving dose.
Due to the reactogenicity (common adverse reactions and “hopes” of the vaccine, especially excessive immunological responses), there was less than the second dose.
The multicentric, controlled and placebo drives, se llevaron a cabo aleatoriamente en adultos sanos de entre 18 y 55 años; as well as in mayors of 65 years or more to receive the vacuna ad26.COV2.
The reactive of Johnson & Johnson can sobrevivir at least 20 degrees centigrade and last three months, always and when to keep temperatures between two and eight degrees; therefore, does not require dilution to apply.
LP