Immunological therapy based on modified proteins, the future treatment of multiple myeloma

Thanks to the various medical advances it is possible that therapies are based on linfocitos T that can be modified and reduce the effect of the cancer.

Dr. Cristian Rodríguez, oncologist.
Dr. Cristian Rodríguez, oncologist.

Eduardo Najar
Agencia Latina de Noticias Medicina y Salud Pública

Multiple myeloma is an affection that has a large number of treatments, without embarrassment, to be able to read a therapy completely effective requires first exams to validate what type of procedure is adequate for each patient, process in the manner of individualized agreement with the necessity of each one.

In an interview with the journal Medicine and Health Public (MSP), the doctor Crsitian Rodriguez, hematologist oncologist, found in the treatment of multiple myeloma, the order that needs to be agreed upon the remission of the patient and the new therapy that is the end of incrementing a mayor effectiveness.

“There are several stages of treatment with multiple myeloma, a monoclonal gamma-ray disease that is an insignificant stage that can be observed in the patient and left following. (…) There are more specific criteria for existing donor or human organs at this point, it should be considered that the patient should be treated sometime to avoid more malignancies in the organism, ”said the doctor.

Immunological treatment

One of the new therapies that is estimated to be used in the future, is by using the modification of linfocitos T, where specialists can manipulate this cell and create a protein that adheres to a similar one that has multiple myeloma, of this therefore, if we eliminate those impulse molecules of the pathology, without embarrassment, this treatment is necessary for validation for this typology of cancer.

Siguen appears to have monoclonal antibodies that try to calibrate proteins or agents such as CD38, which are conjugated to chemotherapy (…). On the other hand, currently, there is a therapy that can manipulate the immune system, which is what it takes to bind foci. attacking the myeloma, then inserting it into the patient and destroying the cell that is required, however, without the need for validation ”, said the specialist.

Division of treats with milk

For a treatment against multiple myeloma effective, requires an evaluation, predominant in groups: the first for those patients whose transplant is and the other for those who do not, is realized with the end of the drug The pharmacists use the properties and do not have any systemic calamity.

“Treatments are divided into two parts, those candidates for transplantation and those who do not, those who can be sometimes in this procedure use three medications: revlimid, bortezomib and dexamethasone, this same regimen is used in other patients. The radical difference is that other treatments can be used for the second group, ”says the doctor.

Shifts and orders in medicines

As the doctor explains with regard to treatment determinations, a large amount of remission should be given to the patient, without embarrassment.

“When there is a remedy in nursing there is no specific order, it is important to understand what medications the remedy is being resistant to and at what time, with the end of being adequately recommended for the second line of therapy. También also needs to take into account the secondary effects of the patient, in order to realize the respective change, ”concluded Dr. Rodríguez.