I’m worried that humans will be infected again by some of the new strains of the coronavirus

I’m worried that humans will be infected again by some of the new strains of the coronavirus

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We’re never going to be done with this damn pandemic. Ever.

Today’s Groundhog Day, right? Well, let me quote the viral prediction: ‘It will be cold, it will be gray and it will keep you for the rest of your life.’

Because I’m stupid, it did not automatically occur to me that a mutant strain of the virus that produces antibodies produced by a first-generation version of a vaccine can also avoid antibodies produced by a first-generation version of a vaccine. the virus itself. If you were infected with the common coronavirus a few months ago and get over it, there is no logical reason why you will necessarily be protected by a new strain that is so sufficient that your body’s immune system can no longer “recognize” it. . Which, according to Fauci, is exactly what is happening in South Africa. People who have had COVID 1.0 get COVID 2.0 thanks to the variant that appears there. Take a look at a few minutes here.

It is not just South Africa where people seem to be infected again. Manaus, a city in Brazil, was destroyed by COVID last year. The reward for enduring a savage outbreak is the immunity of the flock among the survivors – unless the virus mutates to the point that it is effectively a new pathogen again, in which case there is another violent outbreak on the tap. It seems that Manaus is now facing:

Even in a year of terrible suffering, what is happening in Brazil stands out. In the rainforest city of Manaus, where 2 million people live, bodies are apparently being dropped into mass graves as quickly as possible. The hospital’s oxygen is running out, and people with COVID-19 cases that may be treatable are dying of suffocation. This nature and extent of death has not been seen since the first months of the pandemic …

Data seem to support the idea that herd immunity is close in Manaus. In Science this month, researchers mapped out the virus’ takeover last year: in April, blood tests found that 4.8 percent of the city’s population had antibodies to SARS-CoV-2. By June, it was 52.5 percent. Since people who become infected are not always positive on antibodies, the researchers estimate that about two-thirds of the city was infected by June. By November, the estimate was about 76 percent. In The Lancet this week, a team of Brazilian researchers noted that even if these estimates are not large, infection at this scale should ‘grant important immunity to the population to prevent a major outbreak’. It did indeed look like that. The city was able to largely reopen and remain open throughout the winter with low COVID-19 cases.

Either scientists greatly overestimated the share of the population that was granted immunity to the initial outbreak, or the new Brazilian variant was burned by people recovering from ordinary COVID. The best situation for us: we may need a shot several times a year for vaccine increases, as new strains emerge here or abroad and begin to spread among the population, including among people who have had the disease before. (Modern is already developing a stimulus for the South African variant, and Pfizer ‘lays the groundwork’ to do so if their current vaccine finally struggles against the strain.) The worst-case scenario: a super-infectious strain emerges and begins to break through Lightning fast in America as pharma scrambles to develop and distribute a booster, let us once again focus on the immunity of the herd.

We may not need a “permanent” vaccine infrastructure to make this happen, but a short-term mobilization after which everything will return to normal in September as wishful thinking.

In fact, the Times reports today that the highly contagious British strain of the virus could develop to withstand current vaccinations. Pfizer and Moderna recently reported that they believe their products are just as effective against the current UK variant as against COVID. But what about the ‘new’ British variant?

Scientists suspect that the B.1.351 [South African] The partial escape of the vaccine variant is largely due to a single mutation called E484K. Experiments indicate that the E484K mutation makes it harder for antibodies to reach the virus and prevent it from entering cells.

Now it seems that some B.1.1.7 coronaviruses in Britain also have the E484K mutation…

[I]In a report posted online on Tuesday, Rajiv Gupta, a virologist at the University of Cambridge, and his colleagues reported an experiment to address exactly this question. They combined the E484K mutation with other key mutations found in the B.1.1.7 variant, the original in Britain. The addition of the E484K mutation made it difficult for the antibodies to block the viruses. The researchers wrote that they “observed a significant loss of neutralizing activity”.

If you liked the British super-corona, you will love the British super-super-corona. Now look why Fauci and the CDC encouraged people to double-mask? It’s not because Fauci is a killjoy that will not rest until we all walk around in moon suits. This is because the foreign tribes are already circulating here and it seems unlikely that we will vaccinate a significant number of people before they have done a lot of damage. If supercorona spreads more easily than corona, the obvious thing is to add extra filtration to your airways to prevent it from inhaling.

I leave you with a hopeful remark from former FDA chief Scott Gottlieb, who thinks SARS-CoV-2 is mutating slowly enough so that we can stay ahead of it with an aggressive vaccination regime. It is important to note that although the South African and Brazilian tribes may seemingly re-infect humans, the jury is still investigating whether it is more contagious than ordinary COVID. The British variant apparently has the advantage because it quickly became the dominant tribe in the United Kingdom, but the other ominous tribes may not spread as quickly. It’s just a little harder to deal with common antibodies. Starting question: Why, according to the FDA, is it going to take “weeks” to decide whether Moderna can fill his vaccination dishes with 15 doses instead of 10, as he wants? This is an immediate increase in production of 50 percent. And time is of the essence.

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