(CNN) – Ian Haydon helped try the vaccine against Moderna’s coronavirus last year. Now collaborate to try the modified version of this vaccine designed to combat a new and more contagious variant.
“One year ago, the Moderna vacuna tried to be safe. (Bederf: There it is!) Now, in my #COVIDvaccine anniversary, I’m happy to share that I’ll get a third dose. This refueling experiment reveals (1) that the vehicles adapted to the crews increase and (2) their security, “said Haydon, a communications specialist at the University of Washington, on Twitter.
“It is not clear if this new modified version will be necessary,” Haydon confirmed to CNN in a telephone interview.
“But it’s unfolding and trying at this moment for the connection to mano.”
According to doctors, the coronavirus can be terminated after the flu, which requires a new vaccine every year, as long as the fast-moving cephalopods before the vaccine disappears rapidly.
Although the initial evidence suggests that vaccination against coronavirus promotes prolonged protection, vaccine manufacturers have begun to manufacture and test versions of vaccines that protect against virus variants. This includes version B.1.351 identified by the first time in South Africa, which carries a mutation that, in laboratory experiments, may allow a small human immunodeficiency to occur.
The most recent informant of the Pfizer manufacturer shows that people in South Africa receive their vaccine against the coronavirus when B.1.351 converts to the dominant circulating virus, which institutes highly protected infections, even if the laboratory experiments are correct. he demonstrated that the vaccine causes a strong reaction that proportions a patch against the effects of the virus’ mutations.
“Everything is simply what we call good protection,” said Scott Hensley, immunologist and expert at the University of Pennsylvania.
But car manufacturers are not arriesgan. It follows that Haydon’s participation will only test a third dose of the Modern vaccine adjusted to protect specifically against B.1.351 –It is only obtovo–, we also have a third dose of the original vaccine in some voluntary cases, to be seen the potential humanitarian response is secure and offers a sale.
A report published by Pfizer suggests that people receiving both doses of fluids during their months. The experts are desperate to signal that this does not mean that the immunization will take place in six months. Meaning that he has been following the volunteers of the ensembles for a longer period of time in order to see them in his possession. It’s likely to cost a lot more, says Hensley.
“I’m not surprised if we’re inside one year that these vacancies still produce a strong response,” Hensley’s director told CNN.
“Nee my surprendería que esta see una vacuna que solo recibimos una vez”.
It is said that the carcass appears more closely on the carcasses than the carcasses against the flu. The vaccination against the sarampi protects against the infection of life in 96% of the persons.
Pfizer dose vaccine protection is maintained at around 91% inclusive for six months, according to the company. Has given the details in a communication, not in a formal scientific publication, and the dates cover only a few miles of people. But if it is a mantle, it is an indication that both Pfizer’s vehicles, like Modern’s, are provoking a lasting response, experts say.
Hensley explains that the technology used for both vacancies, the genetic material conjugate associated with ARN’s ARNm message, is particularly potent.
“The antitrust responses to these ARNm vehicles are extremely high. What we have in animal models with other ARNm vacancies that have been tried before is that their antecedent responses have been drastically increased and have not decreased over time, ”said Hensley, whose laboratory tested ARNm’s experimental vacancies.
Although the vaccines against the coronavirus are, by supuesto, new (the virus only exists since the end of 2019), ARNm’s technology has been studied for several years and has been used to produce vaccines against the flu, the Ebola and the virus del Zika.
Various studies have indicated that there is a vacancy against the coronavirus.
In addition, a team led by the Dra. Alicia Widge at the National Institute of Allergy and Infections Infected writes in the New England Journal of Medicine that his research showed that doses of the modern vaccine produced many anticoagulants that decreased significantly with time. The vaccine also shows that the body produces cellular cells known as cells T and cells B, which can maintain active defenses during years. Discover that the immune response induced by the vaccine is more powerful and less variable than the immune response that results in a natural infection.
Another study in the New England Journal of Medicine in February revealed that the extraction of people receiving the vaccine against the cofid-19 of Pfizer / BioNTech continued to produce an immune response against variant B.1.351.
“Although we do not know exactly what level of neutralization is required for protection against infection by covid-19, our Experience with other vacancies tells us that it is probable that the Pfizer vaccine provides a relative protection currently a CNN Scott Weaver, director of the Instituto de Infecciones e Inmunidad Humana de la Rama Médica de la Universidad de Texas.
However, in recent months, South African virologists have argued that there is a growing body of evidence that vacancies do not work well against B.1.351 and require car manufacturers to start adjusting their formulas.
You must also have Haydon participate in clinical trials that require periodic blood extractions to test your immunity, have no idea what is well protected against the virus.
“If it’s the principle of the assay, all participants and you develop neutralizing antiquities, of the type that bushes. “I’ve been clear about this for many, many months,” commented Haydon. “But the level of their antiquities, and the levels I changed with time, is not something that I digan. It is one of the main things that will be evaluated during the study ».
There must be a strong reaction to the first round of evacuation and then the third dose that acababa will receive will also cause some effects.
“Como una gripa, es la forma correcta de beskrywe mis síntomas”, dijo. “Ended with fever, scallop fever, a pimple, nausea,” he added.
Immunologists say that it is a signal that the immunological system responds to the vaccine, even if the persons who are not informed also develop an immunization, for which the immunosuppressants suggest that some have more than enough.
Haydon does not know if his answer is that he says anything about the level of immunity that exists from the first dose applied one year.
What he knows is that he can not behave as he does completely completely. If you have used any mascara each time you have avoided any of these routes.
“We live in a world where the mayor of the people is not vacated. The hecho of those who have been vacated has not changed everything for you », says Haydon.
“Everybody wants to take a lot of the precautionary measures that a person does not take,” he said. Although the risk of going to the hospital decreases considerably, the spread of the virus is an important concern. It has not been long since we began to recover data (which must) that the evacuated persons also transmitted much less the virus. It’s a recent discovery and a very good season ».