The Ministry of Health and the Autonomous Communities will study a giro on the evacuation strategy and withdraw the administration of the second dose of Pfizer and Modern vacancies, which have now been inactivated in the first 21 and 28 days, respectively. Some autonomous organizations, such as Catalonia, Madrid and Andalusia, have complained about the second pinchaza and Sanidad have proposed to debate, presumably this March in the Public Health Commission, the possibility of administering the second dose has been less than 80 . The mayors of this oath — 98% have received a dose and 58% have completed the full measure — receive the second pinchazo in the regular place.
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The three vacancies that are currently being administered — those of Pfizer, Moderna, and AstraZeneca — require doses to increase complete immunization, albeit with the first pinchaz the level of efficacy and elevated: a study of the United States Control Center revealed that the efficiency with a dose of the vacancies of ARN messenger (Pfizer and Modern) is 80% (and 76% in the AstraZeneca). The tropical and paranoid sequences in the retrieval of retrievers in the summit or secondary effects investigations have reached some autonomous levels – Madrid and Catalonia pedian from 21 to 42 days the second pinchazo – claiming to be one agundant dose number of persons receiving the first and second, even before, some degree of protection. “Spacing the vacancy allows time to immunize more people”, justifies the week passed by the Catalan councilor of Salud, Alba Vergés.
Approved, the proposal gives a boost to the evacuation strategy, in line with the decision adopted from the first moment, for example, by the United Kingdom with the evacuation of AstraZeneca (the second dose is 12 weeks). During the month there has always been a discussion between completing the technical file and inoculating the doses to confer the mayor protection possible to the most vulnerable or advance a single pinchaz to the mayor number of persons to have a larger protection column, in addition to forma individu, esa defensa geen see total. France and Italy, for example, also had the green light to increase the second-place dose in the first 42 days.
The proposal for a debate, advanced by the Cadena SER, will be discussed predictably this March at the Public Health Commission, which will represent the Ministry and the autonomous managers of the public health charter. The initial proposal referred to the autonomies, which exemplifies the separation between dose and as is the case in the same week in minorities of 79 and minorities of 69, tend to be approved also by the Interterritorial Council of Health, where participant the Minister of Health, Carolina Darias, and the autonomous health advisers. Health has not concretely been its official position in this sense. ‘Hay and do not debate the documents of the boy borradores. It is not good to discuss drills because we mediate the position of the technicians. There is a high level of alertness with techniques that are debating the possibility, interest and usefulness of space dosage. And there is a public health commission that has to approve the decision on technical decency. The director of the Center for Alerts and Emergencies, Fernando Simón, pointed out that this is because there are tens of thousands of drones.
Up to 42 days, you can withdraw the second dose. Possibility of retreating hay. A first dose offers a more than enough protection, all for the grave forms, against which the star is clearly protected “, said Amós García, president of the Spanish Association of Vacunology. The expert considers that the medium “can be a good strategy within a context of deficit of vacancies”, but matiza: The ideal is to complete the technical sheet. And it appears that there will be a huge amount of Pfizer vacancies and it is also the tendency to take it into account and evaluate before deciding ”.
To Daniel López-Acuña, conductor of Emergencies of the World Health Organization (OMS), returns the second pinchazo also week is, in its juice, “inadequate”: “Return to 42 days [seis semanas], which is something that exemplifies the technical sheet, is one thing: it is an efficacy venture based on the assays, which it is that we have to guide. Pero retraar a ocho semanas es otra cosa distinct, en enmends the restrictions of the technical sheet of medicine without a solid evidence. Querer hacer quickly creates the number of vacancies possessing the dose is not adequate ”. According to Marcos López Hoyos, President of the Spanish Society of Immunology, the media does not impact protection. “More than 42 days have not been demonstrated, there is no clear evidence, but he has nothing to do with it. There are studies where the anticoagulants are from the first dose aguantan, at least, three months. There is no date that suggests protection, ”said López Hoyos.
Health care also depends on deciding what to do with people under 60 years of age who receive the first dose of AstraZeneca’s pharmacy. Tras confirms the small association frequent of the vaccine with blood clots, Health and the communities agree to limit the immunization with this prepared only the persons between 60 and 69 years. Pero fails to clarify what happens to the minors of that oath who have not completed the vacancy. The options being studied are receiving a second dose of another vaccine, as he decided countries like Germany or France; do not inject the second dose, if the primary protector effect is elevated, then discontinue the second pinch of AstraZeneca.
Combination of vacancies
Recently, the Carlos III Institute (ISCIII) launched the CombiVacs study, which evaluates the possibility of administering a dose of the vaccine against the cofidio of Pfizer or Modern in persons who have received only one dose of AstraZeneca. The team recruited 600 men under 60 years of age when they administered a pinchaz with the Anglo-Saxon pharmacy and the plan was to have this second injection increase the level of anticonvulsant: 400 were injected with a second dose of Pfizer immediately the other 200 will be the control group, and the proponents will receive the vaccine 28 days later if the results in the favorable intervention group. “If we are allowed to know the duration of the effect, what impact does it have in repeating the retrieval of a knife and what is the magnitude of the intensification of humorous munitions after one second dose”, José Antonio Frías indicated. , Coordinator of the ISCIII Clinical Investigation Board.
The recruitment of participants will take place on weekdays. “The first is to identify that alternative we can offer and the second corresponds to the public health authorities incorporated in the evacuation strategy,” explained Raquel Yotti, director of the Carlos III Institute.
In a video, the director of the Salud Carlos III Institute, Raquel Yotti, announces the study in which Pfizer’s Moderna’s application is being evaluated and who will receive the first dose of AstraZeneca.
With information from Silvia Ayuso y Daniel Verdú.