(CNN) – Two different teams of investigators will be present this week to find in New York City and other parts of the northern part of the United States a new coronavirus variant that is preoccupied. It is a mutation that the ayadan evades the natural response of the body, as well as the effects of the treatment with monoclonal antibodies.
The genomics investigators named the variant B.1,526. Appearance in people affected by various New York City cities, dijeron, and is “dispersed in the north”.
One of the mutations in this variant is the same as the pre-occupant cambio found in the variant that is first seen in South Africa and is known as B.1,351. También also wants to evade, in short, the response of the corpse to the vacancies. And it’s becoming more common.
“We are observing a constant increase in the detection rate since the December finals last February, with an alarming increase of 12.7% in the last two weeks”, writes a team from the Medical Center of the University of Columbia in an informa which has not been published yet is expected to appear in pre-release version this week.
It is the last of a number of viral variants that he has surpassed in EE.UU., which has registered more cases of coronavirus (28 million) that any other country and where the propagation has been intensified.
It is “of course own, presumably in New York”, said by e-mail the Dr. David Ho, director of the Centro de Investigación del Sida Aaron Diamond in Columbia, who directs the study team.
The viruses mutate all the time. The more people are infected and the longer they are infected, the mayor will have the probability that the virus will change. The body of a patient is loaded with millions of copies of a virus and it is possible that it changes ligament or mutation. The majority will speak as if they were.
But sometimes a mutation or pattern of mutations occurs and is transmitted. If the viruses with patterns are more common vuelven, they are denominant variants. Newly, it is not uncommon for surjanic variants, but it is one of the viruses preoccupied with viruses, like a mayor transmitting or the ability to evade treatments and vacancies, are entities when the comedians take precautionary measures.
The mutation in this variant that most preoccupies investigators is called E484K and it gives the virus the ability to superior part of the body’s humanitarian response, as well as the authoritative treatment with monoclonal antibodies. This mutation appears to be Independent in many different cases, but also appears in a particular variant: the Llamada B.1,526.
“It’s a novelty that is surprising, in an alarming way, in our patient population during the last weeks,” the Columbia team wrote in a copy of its proportion to CNN.
«We find that the detection case of this new variant is increased during the last weeks. A preoccupation is that it will start to surpass other types, just like the variants of the United Kingdom and South Africa », Ho told CNN.
“Prohibition of probes, no tenemos is sufficient dates to confirm this point now”.
For the E484K mutation there are at least 59 different lines of coronavirus, dijeron, which means that it is evolving in independent form throughout the world and everywhere in a known phenomenon with convergent evolution. Puede liefling una ventaja al virus.
“Everything we know about this key clause suggests that we should escape the pressure of the antiquities,” said Ho.
Separately, a team from the California Institute of Technology said they were developing a software that also detected the B.1,526 increase in New York. “It appears that the frequency of line B.1,526 has increased rapidly in New York”, wrote in a pre-printed document, an information that has not been revised by pares since it was published online.
Other variants in California
On Tuesdays, teams will be informed about other variants that will be on sale in California.
Temen que la variant en solo sea más contagiosa, sino que también pueda causa una enfermedad más grav. However, with the information from New York, its investigation is taking place in its first stages, has not been published or revised by parishes and requires more work.
Un equipo de la Universidad de California, San Francisco (USCF), analysis of the virus recipients of California and California and the fact that it is very important. No show took place in September, only the final of the match was held at the meeting of the players.
This variant, which the team llama B.1,427 / B.1,429, has a pattern of mutations different from the variants that were first seen in the United Kingdom, called B.1,1.7 or B.1,351. A mutation, called L452R, affects the protein of the virus, which is the part that adheres to the cells that infect the virus.
A specific mutation, the L452R mutation, in the union domain of the pico protein receptor can allow the virus to accumulate in a more efficient manner to the cells. Our data shows that this is probably the key mutation that has this variant is more infectious “, said CNN’s Dr. Charles Chiu, associate director of the UCSF Clinical Microbiology Laboratory, who directed one of the studies.
And we will find some evidence that there is more pink. “In this study, we observed a mayor pregnant with the association associated with infection B.1,427 / B.1,429, including a mayor risking high oxygen demand”, wrote in his information, which will be published and a pre-impression server this week after public health officials in San Francisco reviewed it.
We want to designate it as a pre-occupation variant and be a priority for the studio.
A second team of Unidos in Salud, a finely organized organization in San Francisco that offers fast food in the San Francisco Mission District, examined 8,846 people during the month of January and sequenced the virus from 630 of the masters . We will also find a rapid increase in the variant.
“The results of the Indian investigation show that the L452R variant represents 53% of the positive sample samples collected between the 10th and 27th of January. This is a significant increase since November, when our sequencing indicates that this variant comprises only 16% of the positive tests “, said in a statement to the Dra. Diane Havlir, an expert in infectious diseases in the USCF who is helping to direct the study.
Havlir’s team is also preparing the halls for its publication.