Japanese scientists have identified stem cells that are essential for hair regeneration, with the aim of conducting clinical research to apply the cells to baldness therapy in men.
According to an article published online in the British journal Scientific Reports, Takashi Tsuji, a team leader at the Riken Research Institute, and colleagues introduced in vitro culture systems and found through functional analysis that stem cells are positive for antibody CD34 and integrin . alpha 6 and beta 5, both adhesive proteins, play an important role in ongoing hair regeneration along with a glycoprotein called tenascin.
“The loss of hair or teeth is not life-threatening, but it does affect the quality of life,” Tsuji said. “I hope to start clinical studies soon.”
The beginning of the biotechnology Organ Technologies Inc. did preparatory work for the launch of the study with partners until the work was suspended last fall, mainly due to the resurgence of the coronavirus pandemic.
Riken is now asking for donations and is looking for partner companies to implement regenerative medicine for those who have lost their hair and teeth.
In the proposed clinical research to cure male pattern baldness, Tsuji’s team plans to grow hair follicles from those with the condition using a method it developed in 2007, and then re-implant the cultured cells in their heads. .
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