Global preoccupation with the Brazilian variant of coronavirus: all you need to know about the new cepa

A patient was transported to Manaos (Michael DANTAS / AFP)
A patient was transported to Manaos (Michael DANTAS / AFP)

A new variant of coronavirus harvested in the coronation of the Brazilian Amazon has sought to raise the international alert. Scientists are now trying to describe the mysteries of this variant identified in this country and that can be more infectious, even if it is known to her.

There are indications that the building as P.1 is one of the factors behind the explosion of COVID-19 cases in Manaos, the capital of the state of Amazonas, where the sanitary services are completely disembarked.

With a maximum number of mutations, también is studying if Brazil is the most beautiful pink which variants are found in the United Kingdom and South Africa, which are the most prevalent in the World Health Organization (WHO).

In the midst of this hallucinogenic preoccupation, the volcanic pandemic has swept through all of Brazil, accumulating 222,666 deaths and 9.1 million cases, according to official data.

¿DÓNDE Y CUÁNDO APARECIÓ LA VARIANTE BRASILEÑA?

The first voice of alarm the animal las Japanese authorities the 9th of January, after analyzing the patterns of the four passengers who were to travel to Tokyo one week earlier, would pass a time on the Amazon.

A preliminary study by the Oswaldo Cruz Foundation (Fiocruz), a Latin American reference medical research center, indicates that this new variant is a “recent phenomenon”.

Probably developed in December and evolved from variants that are circulating in the Amazon.

De hecho, by Manaos he detected about 30 variants of the coronavirus, but the most incriminating is the P.1, according to Efe José Eduardo Levi, researcher at the Institute of Tropical Medicine of the University of Sao Paulo (USP).

There are indications that the building as P.1 is one of the factors behind the explosion of covid-19 cases in Manaos, capital of the state of Amazonas, where the sanitary services were completely disembarked.  EFE / Federico Anfitti / Archive
There are indications that the building as P.1 is one of the factors behind the explosion of covid-19 cases in Manaos, capital of the state of Amazonas, where the sanitary services were completely disembarked. EFE / Federico Anfitti / Archive

WHAT’S THE CHARACTERISTICS? DO YOU HAVE ANY MUTACTS?

Según Fiocruz, the variant of Manaos accumulated in a brief space of time “a number of genetic alterations performed by the communeVarieties of them in the protein “spike” (spike), from which the new coronavirus is needed to enter human cells.

He identified 12 mutations exclusively in this protein “spike” of the Brazilian variant, three of them specifically preoccupied: K417N, E484K, N501Y.

¿ES MÁS CONTAGIOSA?

These three conjunctions of letters and numbers represent amino acids of the “spike”, which mutation is associated with a mayor power of transmission. Ayudarían says the virus replicates more and is more closely linked to the cell’s receptor.

“As if they were a girl, that is the cell, and the heart, that is the receptor. And now there is a virus that can easily kill this virus. If you want to get in shape more easily increase the power to be more infectious”, Indica a Efe Felipe Naveca, virologo del Instituto Leônidas & María Deane (Fiocruz Amazonía).

For another store, it is known that this new variant produces more serious cladding frames.

WHAT IS THE POTENTIAL OF REINFECTION?

Currently there is a case confirmed by a person who contracted the coronavirus in March 2020 and was infected by the Amazon variant, to keep anticurpose.

“It simply came to our notice then that the virus had escaped the antidote to the virus so that it could not be neutralized. It’s in the studio, ”said Naveca.

Workers inside a person killed by covid-19, in the public cemetery Nossa Senhora Aparecida in Manaos, Amazonas (Brazil).  EFE / RAPHAEL ALVES / Archive
Workers inside a person killed by covid-19, in the public cemetery Nossa Senhora Aparecida in Manaos, Amazonas (Brazil). EFE / RAPHAEL ALVES / Archive

SIMILAR GUARDS WITH BRITAIN AND SOUTH AFRICAN?

Brazil is not surging from Britain or South Africa.

The three evolutionary ways of the Independent and surgery is performed sporadically in the three regions, although it has been found that some of the mutations identified in the “spike” protein are the same.

“We believe that we are more contagious about having this mutation in common than increasing transmission,” said Levi, a virologist in the DASA laboratory.

Levi created the Brazilian powder to be the most “pink”, at least for the number of mutations identified in the “spike” protein: 12 fronts to the 8 found in Britain or the 10 of the South African.

¿LA VARIANTE AMAZÓNICA ESTÁ DETRÁS DEL COLAPSO EN MANAOS?

The numbers say yes, but the series does not cause the chaos in the Brazilian Amazon capital.

The samples analyzed in December by Fiocruz detect P.1 in 51% of cases. This percentage has disappeared up to 91% in January, indicating that it is rapidly expanding and has converted to the predominant line in Amazonas.

However, Manaos’ tragedy also contributed to other factors. In these months there is a mayor circulation of other respiratory viruses in the Amazon region, as well as influenza, complemented by a social support of the distance media in Christmas parties.

All of this, united with the new variant and the Amazon hospital infrastructure infrastructure, has provoked the collapse of its health care system and an increase in oxygen for the serious patients that may have caused more deaths.

The Minister of Health of Brazil, Eduardo Pazuello, is being investigated by them.

A patient is experiencing medical attention at the Hospital 28 of August, the 14th of January of 2021, in Manaos (Brazil).  EFE / Raphael Alves
A patient is experiencing medical attention at the Hospital 28 of August, the 14th of January of 2021, in Manaos (Brazil). EFE / Raphael Alves

¿HOW RIESGO OF AN AGRAVAMIENTO LA LA PANDEMIA IN BRAZIL?

According to the experts consulted, if this new variant is used throughout the territory, which can be uncorrected, it is possible to aggravate the delicate sanitary situation of the country.

The ex-minister of Salud Luiz Henrique Mandetta, who was sent to a full pandemic by President Jair Bolsonaro to defend Islam, warned in an interview with a local television station that the new variant can provoke a “mega-epidemic” in 60 days, if it is not mediated.

At the moment, in Brazil, driving from the Amazon, he has detected three imported cases of the variant in the state of San Pablo (sureste), but the number can be much mayor.

WHAT OTHER PACE HAS BEEN DETECTED?

According to the World Health Organization (WHO), cases of this new line have been identified in other Brazilian countries: Japan, United States, United Kingdom, Italy, Germany, South Korea and Ireland.

Some of these nations and others, such as Portugal, Peru, Turkey or Colombia, have suspended Brazilian flights before the fall of P.1.

HAVE HIS EFFECTIVE HOLIDAYS?

Varieties of unrolled vacancies have been reported to be part of the coronavirus “spike” protein.

In this sense, those that are purely based on this protein, the mutations recorded in the British, South African and Brazilian variants “can have an efficacy loss” of these formulas, “only no total”, consider Levi.

Todavía has not published any performance studies with the Brazilian variant.

(By Carlos Meneses Sánchez – EFE)

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