Ricardo Maccioni (74), doctor at Ciencias Médicas de la Universidad de Chile, y at Biomedicina de la Universidad de Colorado, has dedicated a large part of his career to the study of neuroscience, especially in the Alzheimer’s disease. Is known worldwide for its “Unified Theory of Alzheimer’s disease”, which is the position as one of the possible candidates to receive the Nobel Prize in Medicine. In conversation with El Líbero, el medical certificate confirming that it has two nominations, but it will be difficult for it to enter the competence of Latin America.
“It is very difficult to win the Nobel Prize in Medicine in Latin America” dice Maccioni, detailing that in toda la historia un par de argentinos -que ya falecieron- lo han obtenido, “pero nadie en Chile, ni siquiera en Brasil”. It should be noted that there is no Latin American entity that can nominate candidates. “If the Nobel Prize were to be awarded, the city of power would nominate others in the future, other Latin Americans, but this possibility does not exist” afirma el dokter.
Who has the faculty to nominate to receive the gala? The answer is “a very select group”. In the first place, pueden propose numbers of women who have received the prize. We can also create a group of scientists designed by the property Karolinska Institutet de Suecia, awarded the Nobel Prize in Medicine. For the last time, there are 20 universities – also designated by the Academy of Sweden for the Nobel Prizes – which have the potential to nominate candidates, but the list of institutions is very high, for example, there is no Latin America.
20 years ago, Doctor Maccioni resigned as a senior professor at the University of Colorado, United States, where he left his constituent laboratory, when he decided to travel to Chile to conduct the International Center for Biomedicine (ICC), institute created specifically for the country to reach the country.
“Venirme a Chile fue un gran desafío”, relata. “All the people I know are exorcists, because a professional who is well-placed in a developed country in Chile, but I was able to set up a large-scale laboratory”. Currently it is Titular Professor of the Faculty of Medicine of the University of Chile, donate as a media lecturer jornada, in addition to lead the ICC center that agrees with this study case, which allows it to hold its laboratory in the same institution. “It has benefited enormously from the university because of the scientific publications of the center that I hold the number of the U. de Chile”, dice the doctor.
If you consult the scientist, it is possible that the University of Chile patrocin’s his nomination, responding that “no tomarian in account” to the study case, by the requisitions for postal and alguien for the Nobel. In any case, given that this plant, the Universidad de Talca y la Universidad Austral he sent cards to the President of the Republic, pidiéndole que el Estado de Chile patrocine al doctor Maccione, con el objectivat logger más nominations en su carpeta, la cual actuale ya se encuentra en Suecia.
By statute, the State can not make a nomination, in this case, the doctor, but there are groups of civil society that the authorities, like the parliamentarians, conceive the work of Ricardo Maccioni. According to the governor’s support, the doctor said he was more than happy.
But only it is working at the national level. “For a Medical Nobel for Chile”, is a committee which was created about six months ago with the end of potentiating the appointment of Doctor Maccioni, and log in otros scientificos reconocidos a nivel mundial lo nominen también, porque la idea es juntar la burgemeester cantidad de menciones posibles.
This committee has two frames: one that is directed by the doctor Raúl Prieto, which abarca the board of directors of the committee at the national level, and is led by Nelson Reyes, economist, who manages to manage international contacts.
According to Reyes in El Líbero, Roberto Maccioni only has scientific and technical knowledge in the area, meaning that he also “has chemistry with the people, the ability to share information with those who care, and mentor”. It is said that the doctor has trained more than 52 scientists “that he developed well on his own and he made great discoveries at the world level”. In this sense, one of the leaders of the Committee for the Nobel of Chile says “Ricardo has learned to embrace the science of a very apathetic way, but in the end he transmits this passion that leads to scientific challenges to a new generation.”
What this Committee does communicate with scientists and organizations at the world level, who are finally the ones who carry out the nominations. Reyes claims to have spoken to “global world” scientists like George Perry, editor of the Journal of Alzheimer’s Disease; Dr. Harísh Pant, Scientific Emeritus of the National Institutes of Health, and Mark Rasenick, Professor of Physiology and Biophysics in Psychiatry, Director of Biomedicine and Neuroscience of the University of Illinois at Chicago. All of them demonstrated their support for Maccioni’s candidacy. “To me, it is an honor to talk about Ricardo,” Perry and Nelson Reyes point out when he first appeared.
From the Committee “On a Nobel Prize in Medicine for Chile”, the Minister of Social Affairs, Karla Rubilar, acknowledges that she has been rescued and rescued. “Ellos podrían apoyarnos con su red international”, Dollesteen Reyes. Consulted the Ministry of Social Development, opting to not release a version with respect.
“This is a super-important theme for Chile, as the people who need it have good news and their logos will unfold for the first time in history a Nobel Prize in Medicine, it will be all that we have to benefit from everything in the form that we do not have to spend ”, sostiene Reyes.
The scientific hallazgos
Since the last year, Dr. Maccioni has been dedicated to investigating the causes of Alzheimer’s disease (EA) with important contributions to the discovery of tau protein and the cellular mechanisms that underlie it. More important than, its new paradigm that leads to the unified theory of neuroinmunomodulation has rooted in the old conceptions of this disease. According to experts, this is a huge contribution to science and human well-being, and new friends need a reliable and therapeutic diagnosis.
In addition, its contributions have had an impact on the development of innovative approaches to prevention, new therapeutic therapies, as well as the compensation of other neurodegenerative diseases of the human brain.
His laboratory is at the vanguard of the findings of the causes and the new challenges for temperament diagnosis and treatment of Alzheimer’s disease. His contributions are critical to the knowledge of the mechanisms of its Ethiopathogenia, as in the prevention, research of biomarkers diagnostic and treatment of this disease, which is highly valued, considering its enormous impact on the public health.
According to Doctor Maccioni, the Nobel Prize is not based on a scientific career, long data, for example, sin more well for the contributions to the science and works of the hallazgos. “In my case, fundamentally, it is helped by the halllazgos of the protein tau, responsible for Alzheimer’s disease, when it is sobering is this disease ”, dice.
Posteriorment siguo during years warning why protein tau is altered in Alzheimer’s disease, the pathogenesis of the disease, which is found in the brain. Relationships related to “The main hallazgo is rooted in a very old paradigm that impediment advances in investigation and this paradigm was the theory of the microid, which states that the senile places that are made of neurons are the ones responsible for illness ”.
The result of this discovery is that the surge “Unified theory of Alzheimer’s disease”, which plants that the inflammatory process disrupted this pathology. The doctor points out that logarithm measures the help of this hypothesis, “What inflammation has changed is that we need to modify your protein tau”.
“The difference – with other great Alzheimer’s disease investigators – is that we care about the patient from the laboratory lab to the nursing room, and my laboratory works as well, it’s one of the most powerful tools in the world that investigates important lograms that lograms perform in laboratory and clinical practice studies, ”he concluded.