Coronavirus outbreak in nursing home in Kentucky, linked to variant R.1, raises concerns about the impact of the vaccine

According to one of the latest reports from the Centers for Disease Control and Prevention (CDC), a so-called R.1 coronavirus strain variant was detected in an outbreak at a nursing home in Kentucky where nearly all residents were vaccinated. Health departments have noticed that coronavirus infections have surfaced in a quarter of vaccinated residents, raising concerns about the vaccine’s impact.

The unnamed competent nursing home offered all residents and staff vaccinations from January, with 90.4% of 83 residents having a vaccine, and just over half of staff members also accepted doses.

An investigation by the Department of Public Health in Kentucky revealed that an unvaccinated, infected staff started the outbreak in early March, which ultimately resulted in 46 cases of COVID-19. Of the total, 26 residents were infected, including 18 individuals who were fully vaccinated, and 20 staff members, including four vaccinated.

According to the report, individuals who were not vaccinated had an infection risk of 3 to 4.1 times compared to people who accepted jabs.

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The recently approved coronavirus vaccines are safe and extremely effective, but they are not 100% effective, says the CDC, and the agency says breakthrough cases, or infections in people who are fully vaccinated, are expected. However, the effectiveness of the vaccine was lower than the observation of the actual vaccination of vaccines in Israel, although the CDC notes that the results are comparable due to the small sample size, increased risk, and testing regardless of the symptoms in the Kentucky nursing home.

According to the CDC report, the vaccine was 86.5% protective to treat symptomatic diseases for residents, and 87.1% protective among staff. The vaccination was more effective in preventing poor outcomes; the reported vaccine efficacy against hospitalizations was more than 94% for residents; no staff members were admitted to the hospital.

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The R.1 lineage variant is not listed in the CDC’s composite variants of interest or concern, but it does contain several mutations seen in other variants that have been shown in the past to spread faster and resist antibody treatments.

“Although vaccination was associated with a reduced likelihood of infection and symptomatic disease, 25.4% of the vaccinated and 7.1% of the vaccinated were HCP infected, which raises concerns about the possible reduced protective immunity at R.1. , “reads the report. “In addition, four possible reinfections have been identified, providing evidence of limited or diminished natural immunity to this variant.”

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Three residents died, one of whom was vaccinated, and the four possible reinfections were identified among mostly harmless people. All possible cases of reinfection involved symptomatic diseases, and one resident was admitted to the hospital and died.

The CDC insists that the vaccination of COVID-19 among healthcare providers working in competent nursing homes protects to protect residents and prevent virus transmission. The report had limitations, such as potential deviations in the health status of staff members who accepted vaccine versus those who did not, which could skew results that could not control the underlying health conditions. It is also possible that antigen testing missed some asymptomatic cases, which, if true, would affect the effectiveness of the vaccine.

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