PFIZER
WHEN WAS IT APPROVED? 11 December 2020
WHO CAN GET IT? Anyone 16 years or older
DOSAGE: 2 doses, given 21 days apart
HOW DOES IT WORK? Use messenger RNA to deliver a small amount of genetic code from the virus to ‘teach’ the body to produce a protein that triggers antibody production
HOW EFFECTIVE IS IT …
IN 2 DOSES: 95% effective in preventing disease; 100% effective in preventing COVID-19 death; 87% effective in preventing hospitalization
TO FIRST DOSE: (not recommended) ~ 46% effective in preventing infection seven to 20 days later; 57% effective against symptomatic diseases; 72% effective in preventing death; 74% effective against hospitalization; 62% effective against serious diseases (based on data from Israel)
AGAINST VARIANTE OF …
United Kingdom – B117: No significant impact
South Africa – B1351: 10% less effective; still protective
Brazil – P1: 10.4 times weaker antibodies; still protective
MODERNA
WHEN WAS IT APPROVED? 18 December 2020
WHO CAN GET IT? Anyone 18 years or older
DOSAGE: 2 doses, given 28 days apart
HOW DOES IT WORK? Use messenger RNA to deliver a small amount of genetic code from the virus to ‘teach’ the body to produce a protein that triggers antibody production
HOW EFFECTIVE IS IT …
IN 2 DOSES: 94% effective in preventing disease; 100% effective in preventing COVID-19 death; 89% effective in preventing hospitalization
TO FIRST DOSE: (not recommended) ~ 80% effective, based on trial data
AGAINST VARIANTE OF …
United Kingdom – B117: No significant impact
South Africa – B1351: 10% less effective; still protective
Brazil – P1: More data needed
JOHNSON & JOHNSON
WHEN WAS IT APPROVED? 27 February 2021
WHO CAN GET IT? Anyone 18 years or older
DOSAGE: 1 dose
HOW DOES IT WORK? Use a harmless, inactivated cold virus to carry a piece of vein protein into the body to teach it to fight SARS-CoV-2.
HOW EFFECTIVE IS IT …
TO SINGLE DOSAGE: 72% worldwide; 86% in the US
AGAINST VARIANTE OF …
United Kingdom – B117: No significant impact
South Africa – B1351: 64% effective
Brazil – P1: 85% effective