What is known about the Brazilian coronavirus variant, the P1

The Brazilian variant of coronavirus, denominated P1, is slightly known, but desperate alarms in the world because it is most contagious, which has led to various pauses suspending the vicious processes of the South American giant, epicenter of the pandemic.

“The girl is justified, the P1 is a very contagious variant and is propagated very fast in Brazil, because it is a huge country and where the pandemic is taking control”, explained to the AFP microbiologist Natalia Pasternak, director of the Institute Questao de Science.

The P1 appeared in December in the city of Manaos, the capital of the Amazon state, but was only identified as a new variant in January, in Japan, in one of the migrants that flew from that region of northern Brazil.

The variant was also detected in various countries of the Americas, such as Argentina, Chile, Uruguay, Bolivia, Peru and Venezuela. It also applies to the United States, Canada, Germany and France, which announced the suspension of flights from Brazil as well as other nations.

– What is the most contagious? –

Like the South African variant, P1 has the E484K mutation, which can generate more infections than other diseases, due to some studies, because it demands more antibodies to resist the virus.

In addition, there are numerous variations in the protein Spike, in which the virus enters the cells for infectious agents.

“It’s like tuviese a master slave who can open various gates at different times”, observes Jesem Orellana, researcher in Amazonas of the Fiocruz Institute.

“And from an epidemiological point of view, the variant can destabilize regions where it has little control over the circulation of viruses and with poor infrastructure, causing the collapse of hospitals”, as corrected in Manaos, where dozens of patients fall due.

“If the Brazilian authorities hubiesen side responsible, habrían aislado Manaos, as China hizo with Wuhan. Pero in vez de eso, send patients to other regions of the country, with companions, some of them infected with the P1”, lamenta Orellana.

The Brazilian governing body includes “deberia haber cerrado fronteras para avva que esa variante llegase a otros paises, algunos más pobres, como Perú”, agregó.

– ¿Es más letal? –

So far no one was able to send in the perfect solution, which is not strange.

In preliminary investigations, Orellana found that the P1 did not increase the mortality rate in Manaos hospitals, in comparison with the first pandemic, in April 2020.

This analysis val saam met dos stududios published el martes segun los cuales la britainica no deriva en casas más graves de covid-19.

The death toll by covid-19 in Brazil in the last weeks is due to the collapse of hospitals “because this variant is most contagious, but also by the generalized relationship” of the population in front of the prevention media, “song of the media de cuarentena “, agrega Orellana.

Preliminary studies will demonstrate that the Chinese vaccine CoronaVac, the most widely used in Brazil, is effective before P1, as well as Pfizer and AstraZeneca.

– What is the propaganda in Brazil? –

The P1 variant is propagated in all Brazilian territories, although there are no dates that allow it to indicate what percentage is responsible for the contagios in each region.

“The genomic vigilance of Brazil is one of the peers of the world”, in terms of sequencing of the new cepas, “we have not yet discovered the P1 case 60 days ago, in Japan”, quoted Orellana.

The uncontrolled circulation of the virus has given rise to new mutations, with variants of the same virus, as the P2, which circulated in Rio de Janeiro, or the P4, recently detected in Belo Horizonte, in the vecino state of Minas Gerais.

“Brazil is converting into a laboratory of varieties with an open sky”, says Orellana.

To avoid the circulation of these varieties, “the ideal series will have sufficient doses for mass evacuation and a lockdown at the same time, as hiccups in Israel”, agrees the microbiologist Pasternak.

“Pero en Brasil ne tenemos ni lo uno ni lo otro: el confinamiento, principemente, por falta de voluntead politique”, a lo que se suma que “ne tenemos dosis suficientes para la vacunación”, explica la specialist, subrayando la national coordination “of the lucha against the pandemic on the part of the governor of Jair Bolsonaro.

.Source