In an interview with the Journal of Medicine in Public Health the Dr. Luis Delgado, director of the Oncology of the Oncology Hospital of Puerto Rico, talks about the relationship between multiple myeloma and amyloidosis.
El multiple myeloma is a Cancer of the cells plasmatic and produce when cells se vuelven cancerosas y crecen fuera de control. For another part, the amyloidosis ligades cadenas is a trastorno del crecimiento de cells abnormal plasmatic, but with less than cells abnormal plasmatic in the ocean medium in comparison with the multiple myeloma.
Approximately 5-15% of patients with multiple myeloma desarrollan amyloidosis following a series of the Mayo Clinic, the frequency depending on the component M: IgA 2%, IgG 5%, cadence levels 17% and IgD 19% 3.
Burden cells plasmatic that we help defenders of infections are located in the oceanic medium and begin to produce the immunoglobulin for defenders. For this reason, a cascade of reactions is active in our body and future syntomas associated with multiple myeloma which can be a deterrent to hay fever, hypercalcemia, hemoglobin, among others.
The relationship between the multiple myeloma and the amyloidosis is frequently debited to the activity associated with the cells Plasmatic and other studies, patients with powdery mildew develop amyloidosis between 5 and 15%.
The mieloma is much more frequent than the amyloidosis and depending on the patient’s presentation, there is an idea of their diagnosis. For example, the renal case is more evident in those people who padecen amyloidosis, explained the doctor. Además, agregó que esta enfermedad is more aggressive compared to the patient present multiple myeloma.
“In the case of women with which the cutaneous lesion can be most frequent in the amyloidosis”, added the specialist
Treatments
Exist medicines as monoclonal anticoagulants and immunotherapy that function effectively preventing, for example, tumor cellular proliferation. The sobriety of a patient that the teat detector treats the myeloma is approximately five years old, assures the specialist.
“The drugs that are currently being used are more specific and have less severe secondary effects”, the doctor stated
The asteroids always have side pieces for the treatment of cells plasmatic. An alert signal is presented when the person has a renal failure and there is no consequence of being diabetic or any antecedent for this enfermedad. Have patients with multiple myeloma which is asymptomatic and differs from amyloidosis what are you talking about syntomas a la persona, explicit doctor.
Secondary Effects
We have 20 years of current chemotherapy and current chemotherapy medicines has a positive result. In addition, patients receiving intravenous chemotherapy and steroid therapy are interned for three or four days in a hospital setting.
Now the medicine has new generations of proteasome inhibitors with lesser secondary effects, the benefit has been the mayor in amount to the patients he received chemotherapy has a significant response reducing the risk of enfermedad vuelva aparecer.
In addition to chemotherapy therapies, monoclonal anticoagulants have a significant effect in preventing serious secondary effects in conjunction with immunotherapy, activating the immunological system to recognize and destroy them. cells malignas.
Currently using three medicines for the treatment of multiple myeloma and transplants that allow a much better quality of life for patients. The translocation of the medium is a procedure that is performed depending on the comorbidities of the persons and therefore can not be done with all the patients, as in general these procedures are presented in major adults.