The vaccine against Johnson & Johnson’s coronavirus produced a strong protection against serious illness and death caused by COVID-19, and could reduce the spread of the virus by the evacuees, according to the new analysis published online. miercoles by the Food and Drug Administration (FDA door su sigla in English).
The vacancy involves a global efficiency case of 72 per cent in the United States and 64 per cent in South Africa, giving a very contagious variant that now provokes the Mayoria of the cases. South Africa’s efficiencies are higher than previous company published dates.
The vacancy also showed an efficiency of 86 per cent against the grave forms of COVID-19 in the United States, and 82 per cent against grave burial in South Africa. This means that a person evacuated has a very low risk of being hospitalized or killed due to COVID-19.
The analysis confirms that it is probable that the stadiums will benefit from a third vaccine effect against the coronavirus developed in less than a year, and that the request for evacuation will greatly increase the offer. The FDA can authorize the vaccine as soon as possible, depending on the opinion of its assessment panel on the fires, after discussing the published documents.
“With a J&J vaccine, we can accelerate the delivery of the vaccine to our country and to the world,” said Dan Barouch, virologist at the Beth Israel Deaconess Medical Center, who conducted many of the first investigations into the vaccine this year. .
The Johnson & Johnson vacuum can be maintained at normal refrigeration temperatures for less than three months, which greatly facilitates its distribution and comparison with the authorized vacancies manufactured by Moderna and Pfizer-BioNTech, if require dosing and deben almacenarsese at healing temperatures .
But access to the new vacancy could be very limited in principle. Richard Nettles, Vice President of Medical Assistance at EE.UU. of Janssen Pharmaceuticals, Johnson & Johnson’s drug development framework, told legislators on March that several million doses of estrogen were listed to be sent once the FDA authorized the vaccine, much to the dismay of the 12 million that originally compromised to enter the federal government for February finals.
The officers of the Casa Blanca tenian a calculus with more than the Martes, to decree the governors in a weekly parade that includes thousands of estarian doses available the next week, according to a governor of the governor.
Brandnetels says on March that a total of 20 million doses will be listed for the March finals. The company has a contract to add 100 million doses to the June finals.
The Johnson and Johnson booth has a lower efficiency case for the Moderna and Pfizer-BioNTech vacancies, which is around 95 per cent.
But in South Africa, Johnson & Johnson’s vacancy is now the clear winner. The Novavax carcass has a 49-year-old South African fleet. And there is a small body in South Africa of the AstraZeneca-Oxford vaccine that has received a lot of protection. The negative results will lead the South African government to abandon its plan to administer one million doses of AstraZeneca vacancies to health workers. Last week, the governing body began administering Johnson & Johnson’s vacancies on its site, and has now distributed 32,000 more.
The recently published documents, which include the FDA’s first technical analysis on the company’s clinical trial with 45,000 people, present evidence that the vaccine was safe, with notably secondary effects than those of Pfizer and Modern and none. informs of severe allergic reactions such as anaphylaxis.
The protection of the vaccine was consistent with black, Hispanic and white volunteers, and also in different editions. The study indicates a minor efficacy, of 42.3 per cent, for 60-year-olds who had risk factors such as cardiac diabetes or diabetes. Without embargo, this figure is accompanied by a large amount of statistical incidence, according to the FDA.
Although there are several types of vacancies that can protect COVID-19 nurses, it is not clear if vacancies can also prevent people from becoming infected and transmitting the virus to others, as there should be a discussion about speed with society. can return to normalcy after initiating the evacuation campaigns.
The modern team found some indications that the people evacuated had less than a chance of developing an infection without symptoms. AstraZeneca discovers that its vaccine reduces asymptomatic infections in the immediate vicinity.
Johnson & Johnson has been searching for asymptomatic infection mediating anticonvulsants against coronavirus 71 since the aviaries became vaccinated or received a placebo. New analyzes estimate that the vaccine has an efficacy dose of 74 per cent against asymptomatic infections. But this calculation is based on a relatively small number of volunteers, and the FDA signaled that “there is no doubt about the interpretation of these dates and no definite conclusions can be drawn at this time”.
“I believe that the recent evidence that vacancies actually prevent the infection from infestation,” said Barouch.
Carl Zimmer is the author of the column Case. Has published three books, between them She has her mother’s laugh: the powers, perversions and potential of inheritance. @carlzimmer • Facebook
Noah Weiland is a reporter for the magazine and the Washington government, and should not write out so many services of the salud. Creció and East Lansing, Michigan, are completing the la Universidad de Chicago. @noahweiland
Sharon LaFraniere is a periodical investigator. Part of the team that won the Pulitzer in 2018 through its investigations into Donald Trump’s connections with Russia. @SharonLNYT